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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
56 Results for "
CHD
" in MedChemExpress (MCE) Product Catalog:
Products (56)
56 Results for "CHD" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-159989
CAS No.: 3118919-69-7
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UNC10142 (Compound 44) is a first-in-class small molecule antagonist of CHD1 that binds with an IC50 value of 1.7 μM. UNC10142 leads to a dose-dependent reduction in viability in PTEN-deficient prostate cancer cells .
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1 Cited Publications
Cat. No.: HY-141716
Purity: 99.19%
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SW2_110A is a selective chromobox 8 chromodomain (CBX8 ChD) inhibitor with a Kd of 800 nM. SW2_110A shows minimal 5-fold selectivity for CBX8 ChD over all other CBX paralogs in vitro .
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CHD1Li 6.11 is a potent and orally active Chromodomain Helicase DNA Binding Protein 1 Like (CHD1L) (oncogenic gene) inhibitor (IC50 = 3.3 µM for cat-CHD1L recombinant protein). CHD1Li 6.11 can inhibit EMT, induce mesenchymal-epithelial transition (reverse EMT) and promote apoptosis in tumor organoid models. CHD1Li 6.11 can be used for the research of cancer, such as colorectal cancer .
Cat. No.: HY-147058
Purity: 99.77%
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SW2_152F is a potent, selective chromobox 2 chromodomain (CBX2 ChD) inhibitor with a Kd of 80 nM. SW2_152F displays 24-1000-fold selectivity for CBX2 ChD over other CBX paralogs in vitro . SW2_152F is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-N2509
CAS No.: 86849-77-6
Synonyms: Iristectrigenin B
Category:
Cardiovascular Disease Natural Products Iridaceae Phenols Polyphenols Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields
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MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA) MMP-2 inhibitor(IC50=6.6 μM) and can be used for the study of acute myocardial infarction. MMPI-1154 also inhibits the activity of MMP-13, MMP-1 and MMP-9 with IC50s of 1.8 μM,10 μM, and 13 μM, respectively .
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CHD-5 is a potent AhR (aryl hydrocarbon receptor) antagonist .
Cat. No.: HY-P1536
CAS No.: 141685-53-2
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Cat. No.: HY-170565
CAS No.: 3041166-70-2
CHD-1 is a a hypoxia-activated antitumor prodrug. CHD-1 impairs mitochondrial morphology and membrane potential in hypoxic tumor cells, further triggering excessive mitophagy and inducing apoptosis. CHD-1 inhibits the growth of hypoxic tumor cells in vitro and the growth of HeLa xenograft in vivo .
Cat. No.: HY-RS02605
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CHD1 Human Pre-designed siRNA Set A contains three designed siRNAs for CHD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02607
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CHD2 Human Pre-designed siRNA Set A contains three designed siRNAs for CHD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02608
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CHD3 Human Pre-designed siRNA Set A contains three designed siRNAs for CHD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02609
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CHD4 Human Pre-designed siRNA Set A contains three designed siRNAs for CHD4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02610
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CHD5 Human Pre-designed siRNA Set A contains three designed siRNAs for CHD5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02611
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CHD6 Human Pre-designed siRNA Set A contains three designed siRNAs for CHD6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02612
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CHD7 Human Pre-designed siRNA Set A contains three designed siRNAs for CHD7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02613
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CHD8 Human Pre-designed siRNA Set A contains three designed siRNAs for CHD8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02614
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CHD9 Human Pre-designed siRNA Set A contains three designed siRNAs for CHD9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18344
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Chd5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Chd5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21310
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Chd3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Chd3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
