1382722-47-5
Chemical Structure
MMPI-1154
- CAS No.: 1382722-47-5
- Formula:C26H24FN3O3
- Molecular Weight:445.49
IUPAC Name: 2-(((4-(benzyloxy)benzyl)(4-fluorobenzyl)amino)methyl)-1H-imidazole-5-carboxylic acid
InChIKey: QLTNFRCPUOPISS-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(CN(CC2=CC=C(F)C=C2)CC3=CC=C(OCC4=CC=CC=C4)C=C3)N1)O
Biological Activity: MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA) MMP-2 inhibitor(IC50=6.6 μM) and can be used for the study of acute myocardial infarction. MMPI-1154 also inhibits the activity of MMP-13, MMP-1 and MMP-9 with IC50s of 1.8 μM,10 μM, and 13 μM, respectively[1].
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MMPI-1154 | 99.76% | MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA) MMP-2 inhibitor(IC50=6.6 μM) and can be used for the study of acute myocardial infarction. MMPI-1154 also inhibits the activity of MMP-13, MMP-1 and MMP-9 with IC50s of 1.8 μM,10 μM, and 13 μM, respectively. | ||||||||||||||||||||
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Keywords
