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Results for "

CPE

" in MedChemExpress (MCE) Product Catalog:

18

Inhibitors & Agonists

1

Biochemical Assay Reagents

3

Peptides

3

Natural
Products

8

Recombinant Proteins

6

Antibodies

1

Click Chemistry

5

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175469
    VNT-101

    		Influenza Virus Infection
    VNT-101 is an orally active influenza A (IAV) inhibitor. VNT-101 disrupts NP-NP PPI to block NP oligomerization and destabilize the viral ribonucleoprotein (RNP) complex, with potent antiviral activity across multiple influenza A subtypes. VNT-101 exhibits EC50 values of 4-5 nM in cellular cytopathic effect (CPE) assay, 4-8 nM in neuraminidase (NA) assay, and 21-45 nM in RNP assay. VNT-101 demonstrates robust in vivo antiviral efficacy in mice infected with lethal H1N1 virus. VNT-101 can be used for the study of influenza A infection .
    VNT-101
  • HY-12928
    ML336

    		Virus Protease Infection
    ML336 is quinazolinone-based inhibitor against venezuelan equine encephalitis virus (VEEV), with IC50s of 32, 20, and 42 nM for VEEV TC-83 CPE , VEEV V3526 CPE, VEEV Wild Type CPE, respectively. ML336 potently inhibits a VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and wild type Trinidad donkey) in the low nanomolar range .
    ML336
  • HY-121528
    Nilestriol

    Nylestriol; EE3CPE

    		 Estrogen Receptor/ERR Endocrinology
    Nilestriol is a estriol derivative, which inhibits osteoporosis on ovariectomized rats or postmenopausal women .
    Nilestriol
  • HY-P11455A
    Lipopeptide CPE4 TFA

    		Liposome Others
    Lipopeptide CPE4 TFA is a PEG-modified peptide E4 [(EIAALEK) 4]. Lipopeptide CPE4 TFA is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 TFA triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 TFA can be used for drug delivery research .
    Lipopeptide CPE4 TFA
  • HY-124938
    ABC-1

    		Antibiotic Infection
    ABC-1 is a phosphorylated analogue and a potential antiviral agent against Newcastle disease virus (NDV). ABC-1 has potent antiviral activity .
    ABC-1
  • HY-106508
    Fendosal

    HP 129; P 71-0129

    		 PAI-1 Inflammation/Immunology
    Fendosal (HP 129) is an orally active, potent non-steroidal anti-inflammatory agent. Fendosal (HP 129) is also an inhibitor of Plasminogen activator inhibitor-1 (PAI-1) .
    Fendosal
  • HY-P11455
    Lipopeptide CPE4

    		Liposome Others
    Lipopeptide CPE4 is a PEG-modified peptide E4 [(EIAALEK) 4]. Lipopeptide CPE4 is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) (HY-D0815) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 can be used for drug delivery research .
    Lipopeptide CPE4
  • HY-RS03090
    CPE Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CPE Human Pre-designed siRNA Set A contains three designed siRNAs for CPE gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CPE Human Pre-designed siRNA Set A
    CPE Human Pre-designed siRNA Set A
  • HY-RS17120
    Cpe Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Cpe Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cpe gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Cpe Mouse Pre-designed siRNA Set A
    Cpe Mouse Pre-designed siRNA Set A
  • HY-RS23565
    Cpe Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Cpe Rat Pre-designed siRNA Set A contains three designed siRNAs for Cpe gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Cpe Rat Pre-designed siRNA Set A
    Cpe Rat Pre-designed siRNA Set A
  • HY-132169
    HCoV-229E-IN-1

    		SARS-CoV Infection
    HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, with an EC50 of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively .
    HCoV-229E-IN-1
  • HY-174385
    SARS-CoV-2-IN-114

    		SARS-CoV Infection
    SARS-CoV-2-IN-114 (Compound 36) is an antiviral agent. SARS-CoV-2-IN-114 exhibits significant antiviral activity against both the SARS-CoV-2 original strain and the Delta variant. SARS-CoV-2-IN-114 has an EC50 of 0.29 μM for inhibiting CPE of the SARS-CoV-2 original strain, and that for the Delta variant is 5.77 μM. SARS-CoV-2-IN-114 has low cytotoxicity and can be used in coronavirus research .
    SARS-CoV-2-IN-114
  • HY-182731
    Brain CPE

    		Biochemical Assay Reagents Others
    Brain CPE is a sphingolipid found in mammalian cells, bacteria, and invertebrates. Brain CPE is the main sphingolipid found in the cell membranes of fruit flies and houseflies.
    Brain CPE
  • HY-12349
    H1PVAT

    		Enterovirus Infection
    H1PVAT is a potent and selective inhibitor of poliovirus serotypes (PV-1, PV-2, PV-3), and inhibits early stage of the replication. H1PVAT interacts with viral capsid directly and protects PV against heat inactivation .
    H1PVAT
  • HY-P11785
    Cpe30 MT2

    		Claudin Cancer
    Cpe30 MT2 is a short peptide that binds tightly junction protein Claudin‑4 (CLDN4) with high affinity, with a Kd value of 1.97 nM. Cpe30 MT2 can be used for the synthesis of PET molecular imaging probes targeting pancreatic cancer .
    Cpe30 MT2
  • HY-N18293
    Makisterone A 2-acetate

    		HSV Infection
    Makisterone A 2-acetate is a steroid compound that can be isolated from the 75% ethanol extract of Cyanotis arachnoidea. Experimental tests show that Makisterone A 2-acetate has no anti-HSV-1 activity .
    Makisterone A 2-acetate
  • HY-180578
    MWAC-3429

    		SARS-CoV Infection
    MWAC-3429 is a potent SARS-CoV-2 Nsp13 helicase inhibitor. MWAC-3429 inhibits SARS-CoV-2 and SARS-CoV1 with EC50s of 5.39 (nLuc assay) and 17.00 μM (CPE assay), respectively, while showing low cytotoxicity in A549-hACE2 cells (CC50 > 50 μM). MWAC-3429 can be used for SARS-CoV-infection research .
    MWAC-3429
  • HY-180525
    PB2-IN-2

    		Influenza Virus Infection
    PB2-IN-2 is an orally active PB2 inhibitor with RNA-dependent RNA Polymerase (RNP) IC50 = 0.2 nM, LRA (Ligand Receptor Assay) EC50 = 0.8 nM, Cytopathic Effect (CPE) EC50 = 0.1 nM. PB2-IN-2 exhibits broad-spectrum, nanomolar antiviral potency against a panel of influenza A strains (including H1N1pdm09, Lyon/1337/2007/H1N1, Tex12-Like/H3N2, PR/8/34/H1N1, WSN/1933/H1N1, rPR8(H1N1)/H7N9 with EC50 = 1.5, 3.6, 3.7, 13.8, 2.9 and 9.8 nM and all the CC50 values > 2 μM. PB2-IN-2 possesses an excellent pharmacokinetic profile and metabolic stability. PB2-IN-2 can be used for anti-influenza research .
    PB2-IN-2

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