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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
CST 905
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "CST 905" in MCE Product Catalog:
Cat. No.: HY-175435
CAS No.: 3094183-98-6
Research Areas:
CST905 is a potent BRAF-V600E PROTAC degrader with a DC50 of 18 nM. CST905 recruits the VHL E3 ligase to form a ternary complex, mediating the degradation of BRAF-V600E via the ubiquitin-proteasome pathway. The ligand of CST905 disrupts the RAF dimerization interface, thereby preventing the aberrant activation of the harmful MAPK/ERK pathway in RAS-mutated cells while degrading the target protein. CST905 can be used in studies related to malignant melanoma and neuroblastoma .
Cat. No.: HY-78378
CAS No.: 470478-90-1
Target:
Research Areas:
4-(4-Boc-piperazinemethyl)phenylboronic acid pinacol ester is a PROTAC linker that can be used in the synthesis of CST905 (HY-175435) .
Cat. No.: HY-175726
CAS No.: 3094183-96-4
Research Areas:
BRAF ligand-Linker Conjugate 1 is a target protein ligand-linker conjugate that can be used to synthesize PROTAC CST905(HY-175435) .
Cat. No.: HY-41747
CAS No.: 2413037-31-5
Research Areas:
BRAF ligand-1 is the ligand of BRAF. BRAF ligand-1 can be used to synthesize CST905 (HY-175435) .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
