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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
Results for "

Cell Proliferation Fluorescent Probe

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Fluorescent Dyes

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0938
    CFDA-SE
    105+ Cited Publications

    CFSE; 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester

    		 Fluorescent Dye Others
    CFDA-SE is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus . CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
    CFDA-SE
  • HY-DY1009
    CFDA-SE (solution)

    		Fluorescent Dye Others
    CFDA-SE (solution) is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus . CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
    Solvent and concentration: DMSO: 5 mM
    CFDA-SE (solution)
  • HY-155062
    IR-251

    		Mitochondrial Metabolism Reactive Oxygen Species (ROS) β-catenin Fluorescent Dye PPAR Cancer
    IR-251 is a mitochondrion-targeting NIR fluorescent probe. IR-251 targets mitochondria via OATPs and causes mitochondrial damage in tumor cells. IR-251 IR-251 induced ROS overproduction by inhibiting PPARγ, and then inhibiting the β-catenin signaling pathway and downstream protein molecules related to the cell cycle and metastasis. IR-251 inhibits tumor proliferation and metastasis .
    IR-251
  • HY-181506
    TYMJ-01

    		Fluorescent Dye Molecular Glues CaMK c-Myc Bcl-2 Family Cadherin Cancer
    TYMJ-01 is a fluorescent probe and eEF2K degrader. TYMJ-01 induces dose-dependent and specific degradation of eEF2K via the ubiquitin-proteasome pathway, with a DC50 of 82 nM. TYMJ-01 inhibits the proliferation, migration and invasion of triple-negative breast cancer cells. TYMJ-01 enables dynamic fluorescent imaging of eEF2K degradation in triple-negative breast cancer cells; it enhances the anti-tumor activity of Paclitaxel (HY-B0015). TYMJ-01 can be used for the research of triple-negative breast cancer .
    TYMJ-01

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