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Cat. No.: HY-W585368

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BODIPY dye

Name: BODIPY dye
Brand: MedChemExpress
SKU: HY-W585368
Price: 60.00 USD
Availability: InStock
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BODIPY dyes are a class of small-molecule fluorophores with strong ultraviolet absorption and sharp fluorescence emission peaks. BODIPY dyes can non-specifically label erythrocyte membranes, fail to inhibit the proliferation of Plasmodium falciparum, exhibit weak cytotoxicity against Chinese hamster ovary cells, and have extremely low hemolytic activity. BODIPY dyes serve as a universal scaffold for fluorescent compounds such as laser dyes and fluorescent probes, and can also be used to construct photoelectric and biophotonic molecular assembly units. BODIPY dyes are applicable to research related to live-cell imaging, fluorescent labeling of proteins and DNA, and various biological imaging assays.

For research use only. We do not sell to patients.

CAS No.: 945921-51-7
Formula: C₂₀H₁₉BF₂N₂O₂
Molecular Weight:368.18

Storage:

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

BODIPY dye Chemical Structure

CAS No.: 945921-51-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

In Vitro

OthersParasitic Infection

Others

BODIPY dye improves its fluorescence efficiency through selective α-position chlorination of 8-methylphenyl-BODIPY and electron-withdrawing group functionalization on boron center^[2].

Others

BODIPY dye achieves bathochromic spectral shift toward far-red region and reaches maximum fluorescence quantum yield of 65 via extended conjugation with electron-withdrawing aryl substituents^[2].

Others

BODIPY dyes can be functionalized with meso-pyrene or 4-phenylphenol moieties respectively, enabling reversible fluorescent sensing of solvent polarity or environmental pH via ICT or PET processes^[2].

Others

BODIPY dyes induce chiral optical activities, including circular dichroism and circularly polarized luminescence. After forming helical bis-BODIPY via covalent linkage or combining with chiral binaphthol/vapol moieties, vapol-BODIPY acts as a highly efficient FRET-based antenna system^[2].

Others

BODIPY dye bearing iodine substituents generates high-content singlet oxygen under light irradiation^[2].

Parasitic Infection

BODIPY dye (5 μM; 15 min) non-specifically stains both Plasmodium falciparum strain W2-infected and uninfected human red blood cells^[3].

Parasitic Infection

BODIPY dye (100 nM; 24 h) does not alter the morphology of *Plasmodium falciparum* strain 3D7 in infected human red blood cells^[3].

Parasitic Infection

BODIPY dye exhibits no anti-plasmodial activity against *Plasmodium falciparum* strains W2 and HB3, shows moderate toxicity to CHO-K1 cells with an IC₅₀ of 88 μM, and does not induce hemolysis in healthy human red blood cells even at concentrations as high as 100 μM^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

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Chemical Information

CAS No. 945921-51-7
Appearance Solid
Molecular Weight 368.18
Formula C₂₀H₁₉BF₂N₂O₂
Color Orange to red
SMILES

O=C(C1=CC=C(C2=C3C(C)=CC(C)=[N]3[B+3]([F-])([N-]4C(C)=CC(C)=C24)[F-])C=C1)[O-].[H+]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Loudet A, et al. BODIPY Dyes and Their Derivatives: Syntheses and Spectroscopic Properties. Chemical Reviews. 2007;107(11):4891-4932.

[2]. Bañuelos J, et al. BODIPY Dye, the Most Versatile Fluorophore Ever?. Chemical record (New York, N.Y.). 2016 Feb;16(1):335-48. [Content Brief]

[3]. Rice DR, et al. Antiplasmodial activity of targeted zinc(II)-dipicolylamine complexes. Bioorganic & medicinal chemistry. 2017 May 15;25(10):2754-2760. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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BODIPY dye

Biological Activity

Description

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Chemical Information

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References

Calculators

Help & FAQs

BODIPY dye Related Classifications

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