945921-51-7
Chemical Structure
BODIPY dye
- CAS No.: 945921-51-7
- Formula:C20H19BF2N2O2
- Molecular Weight:368.18
IUPAC Name: hydrogen 4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4l4,5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)benzoate
InChIKey: LSGGIECGYIBGDU-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C2=C3C(C)=CC(C)=[N]3[B+3]([F-])([N-]4C(C)=CC(C)=C24)[F-])C=C1)[O-].[H+]
Biological Activity: BODIPY dyes are a class of small-molecule fluorophores with strong ultraviolet absorption and sharp fluorescence emission peaks. BODIPY dyes can non-specifically label erythrocyte membranes, fail to inhibit the proliferation of Plasmodium falciparum, exhibit weak cytotoxicity against Chinese hamster ovary cells, and have extremely low hemolytic activity. BODIPY dyes serve as a universal scaffold for fluorescent compounds such as laser dyes and fluorescent probes, and can also be used to construct photoelectric and biophotonic molecular assembly units. BODIPY dyes are applicable to research related to live-cell imaging, fluorescent labeling of proteins and DNA, and various biological imaging assays[1][2][3].
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BODIPY dye | BODIPY dyes are a class of small-molecule fluorophores with strong ultraviolet absorption and sharp fluorescence emission peaks. BODIPY dyes can non-specifically label erythrocyte membranes, fail to inhibit the proliferation of Plasmodium falciparum, exhibit weak cytotoxicity against Chinese hamster ovary cells, and have extremely low hemolytic activity. BODIPY dyes serve as a universal scaffold for fluorescent compounds such as laser dyes and fluorescent probes, and can also be used to construct photoelectric and biophotonic molecular assembly units. BODIPY dyes are applicable to research related to live-cell imaging, fluorescent labeling of proteins and DNA, and various biological imaging assays. | |||||||||||||||||||||
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- [1]. Loudet A, et al. BODIPY Dyes and Their Derivatives: Syntheses and Spectroscopic Properties. Chemical Reviews. 2007;107(11):4891-4932.
- [2]. Bañuelos J, et al. BODIPY Dye, the Most Versatile Fluorophore Ever?. Chemical record (New York, N.Y.). 2016 Feb;16(1):335-48. [Content Brief]
- [3]. Rice DR, et al. Antiplasmodial activity of targeted zinc(II)-dipicolylamine complexes. Bioorganic & medicinal chemistry. 2017 May 15;25(10):2754-2760. [Content Brief]
Keywords
