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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
Cidofovir
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "Cidofovir" in MCE Product Catalog:
15
15 Publications Verification
Cat. No.: HY-17438
CAS No.: 113852-37-2
Synonyms: GS 0504; HPMPC; (S)-HPMPC
15
15 Publications Verification
Cat. No.: HY-17438A
CAS No.: 149394-66-1
Synonyms: GS 0504 dihydrate; HPMPC dihydrate; (S)-HPMPC dihydrate
6
6 Cited Publications
Synonyms: CMX001; HDP-CDV
Target:
Research Areas:
Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo .
Cat. No.: HY-131606B
Target:
Research Areas:
Cidofovir diphosphate tri triethylamine is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate tri triethylamine is a selective inhibitor of viral DNA polymerases with Ki values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively .
Cat. No.: HY-131606
CAS No.: 142276-31-1
Target:
Research Areas:
Cidofovir diphosphate is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate is a selective inhibitor of viral DNA polymerases with Ki values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively .
Cat. No.: HY-131606S
Cat. No.: HY-14532S
CAS No.: 1917374-64-1
Synonyms: CMX001-d6; HDP-CDV-d6
Cat. No.: HY-17438R
CAS No.: 113852-37-2
Synonyms: GS 0504 (Standard); HPMPC (Standard); (S)-HPMPC (Standard)
Category:
Cat. No.: HY-167911
CAS No.: 127749-27-3
Synonyms: GS 0504 sodium; HPMPC sodium; (S)-HPMPC sodium
Cidofovir sodium is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir sodium inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir sodium induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer . Cidofovir sodium also has anti-orthopoxvirus and anti-variola activities .
Cat. No.: HY-167911S
Synonyms: GS 0504-13C,15N2 disodium; HPMPC-13C,15N2 disodium; (S)-HPMPC-13C,15N2 disodium
Cat. No.: HY-179638
CAS No.: 3059641-72-1
Target:
Research Areas:
Antiviral agent 74 is an antiviral agent consisting of Cidofovir (HY-17438) prodrug and lipid chain. Antiviral agent 74 can inhibit the activity of viral DNA polymerase by transforming into Cidofovir.Antiviral agent 74 demonstrates potent antiviral activity against vacciniavirus (VACV) (EC50 = 0.156 μM) comparable to Brincidofovir (HY-14532). Antiviral agent 74 shows superior potency against monkeypox virus (MPXV) with an EC50 vales of 0.202 μM. Antiviral agent 74 can be used for the research of virus infection .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
