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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Cl-amidine
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Cl-amidine" in MCE Product Catalog:
Cat. No.: HY-100574
CAS No.: 913723-61-2
Research Areas:
Cl-amidine is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine induces apoptosis in cancer cells. Cl-amidine induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .
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24 Publications Verification
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Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .
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24 Publications Verification
Cat. No.: HY-100574B
CAS No.: 1043444-18-3
Research Areas:
Cl-amidine TFA is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine TFA induces apoptosis in cancer cells. Cl-amidine TFA induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine TFA prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .
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11 Cited Publications
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BB-Cl-Amidine is a peptidylarginine deminase (PAD) inhibitor.
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11 Cited Publications
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Research Areas:
BB-Cl-Amidine hydrochloride is a peptidylarginine deminase (PAD) inhibitor .
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D-Cl-amidine hydrochloride is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity .
LB244 is a homologue of BB-Cl-amidine, which is an orally effective STING inhibitor (EC50=0.8 μM) and can be used to inhibit STING-dependent inflammatory diseases. The pharmacokinetic properties of LB244 indicate limited oral activity in mice .
Cat. No.: HY-100574C
CAS No.: 1404060-15-6
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D-Cl-amidine is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity .
Cat. No.: HY-W297348
CAS No.: 1965308-76-2
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(Rac)-Cl-amidine is an orally active peptidyl arginine deimidase (PAD) inhibitor with the property of inhibiting PAD activity. (Rac)-Cl-amidine exhibits enhanced efficacy in cells and can be used to study PAD function. (Rac)-Cl-amidine can effectively regulate gene transcription, cell differentiation and innate immune response .
Cat. No.: HY-111347B
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BB-Cl-Amidine TFA is a peptidylarginine deminase (PAD) inhibitor .
Cat. No.: HY-100574DR
CAS No.: 2985338-61-0
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D-Cl-amidine (hydrochloride) (Standard) is the analytical standard of D-Cl-amidine (hydrochloride) (HY-100574D). This product is intended for research and analytical applications. D-Cl-amidine hydrochloride is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity .
Cat. No.: HY-111347R
CAS No.: 1802637-39-3
Research Areas:
BB-Cl-Amidine (Standard) is the analytical standard of BB-Cl-Amidine (HY-111347). This product is intended for research and analytical applications. BB-Cl-Amidine is a peptidylarginine deminase (PAD) inhibitor.
Cat. No.: HY-111347AR
CAS No.: 2436747-41-8
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BB-Cl-Amidine hydrochloride (Standard) is the analytical standard of BB-Cl-Amidine (hydrochloride) (HY-111347A). This product is intended for research and analytical applications. BB-Cl-Amidine hydrochloride is a peptidylarginine deminase (PAD) inhibitor .
Cat. No.: HY-P11870
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
