3074622-05-9
3074622-05-9
Chemical Structure
LB244
- CAS No.: 3074622-05-9
- Formula:C30H27N5O5
- Molecular Weight:537.57
InChIKey: YJTWDEBBCCREDG-VWLOTQADSA-N
SMILES: O=C(N[C@@H](CCCCNC(C1=CC=C(O1)[N+]([O-])=O)=O)C2=NC3=CC=CC=C3N2)C(C=C4)=CC=C4C5=CC=CC=C5
Biological Activity: LB244 is a homologue of BB-Cl-amidine, which is an orally effective STING inhibitor (EC50=0.8 μM) and can be used to inhibit STING-dependent inflammatory diseases. The pharmacokinetic properties of LB244 indicate limited oral activity in mice[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LB244 | 98.45% | LB244 is a homologue of BB-Cl-amidine, which is an orally effective STING inhibitor (EC50=0.8 μM) and can be used to inhibit STING-dependent inflammatory diseases. The pharmacokinetic properties of LB244 indicate limited oral activity in mice. | ||||||||||||||||||||
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References
Keywords
