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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Colon contraction
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Colon contraction" in MCE Product Catalog:
Cat. No.: HY-W100287
CAS No.: 4532-33-6
Synonyms: MK-678; L-363586
Target:
Cat. No.: HY-167902
CAS No.: 159081-22-8
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YM-31636 free base is an orally active, potent and selective 5-HT3 receptor agonist with a Ki value of 0.2 nM. YM-31636 free base induces contraction of isolated guinea pig distal colon. YM-31636 free base induces tachycardia with the relative intrinsic activity of approximately 0.23 in isolated guinea pig right atrium. YM-31636 free base is promising for research of constipation .
Cat. No.: HY-101303
CAS No.: 190277-13-5
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5-MCA-NAT is a melatonin agonist that may target the melatoninMT3 receptor. 5-MCA-NAT can contract the colonic band in a concentration-dependent manner and reduce intraocular pressure (IOP) in glaucomatous monkey eyes, inhibiting the increase in IOP .
Cat. No.: HY-139119
CAS No.: 68192-15-4
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Prostaglandin F2α dimethyl amide is an antagonist for Prostaglandin F2α (HY-12956), which blocks 50% contraction on gerbilMeriones unguiculatus colon induced by PGF2α at 3.2 μg/mL .
Cat. No.: HY-112707
CAS No.: 3032946-55-4
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AM9405 is a novel peripherally active cannabinoid type 1 (CB1) and serotonin type 3 receptor agonist. AM9405 inhibits twitch contraction of the ileum and the colon with IC50s of 45.71 and 0.076 nM, respectively.
Cat. No.: HY-106323
CAS No.: 59530-69-7
Synonyms: KW-5139
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Cat. No.: HY-123285
CAS No.: 91147-46-5
Synonyms: 5-Desbromo, 5-chloro brimonidine
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UK 14819 (5-Desbromo, 5-chloro brimonidine) is an α2-adrenoceptor agonist. UK 14819 inhibits stimulation-induced contractions of rabbit distal colon with an IC50 of 6.66 nM .
Cat. No.: HY-W100287R
CAS No.: 4532-33-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
