1. GPCR/G Protein Neuronal Signaling
  2. Cannabinoid Receptor 5-HT Receptor
  3. AM9405

AM9405 is a novel peripherally active cannabinoid type 1 (CB1) and serotonin type 3 receptor agonist. AM9405 inhibits twitch contraction of the ileum and the colon with IC50s of 45.71 and 0.076 nM, respectively.

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AM9405 Chemical Structure

AM9405 Chemical Structure

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Description

AM9405 is a novel peripherally active cannabinoid type 1 (CB1) and serotonin type 3 receptor agonist. AM9405 inhibits twitch contraction of the ileum and the colon with IC50s of 45.71 and 0.076 nM, respectively.

IC50 & Target

CB1

45.71 nM (IC50)

5-HT3 Receptor

0.076 nM (IC50)

Molecular Weight

461.44

Formula

C24H33BrN2O2

SMILES

OC1=C(C2=[N+](C)C(C=CC=C3)=C3N2C)C(O)=CC(C(C)(C)CCCCCC)=C1.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
AM9405
Cat. No.:
HY-112707
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