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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Crown ether
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Crown ether" in MCE Product Catalog:
Cat. No.: HY-D0180
CAS No.: 17455-13-9
Synonyms: 18C6; 1,4,7,10,13,16-Hexaoxacyclooctadecane
Cat. No.: HY-W007656
CAS No.: 294-90-6
Category:
Natural Products Other Diseases Plants Disease Research Fields Menispermaceae Stephania japonica (Thunb.) Miers
Target:
Cat. No.: HY-W009048
CAS No.: 16069-36-6
Synonyms: DCH18C6; Perhydrodibenzo-18-Crown-6
Cat. No.: HY-W102545
CAS No.: 31249-95-3
Cat. No.: HY-W008585
CAS No.: 14098-44-3
Synonyms: B15C5
Cat. No.: HY-157914
CAS No.: 106868-21-7
Synonyms: 6,6-Dibenzyl-1,4,8,11-tetraoxacyclotetradecane
Cat. No.: HY-W103245
CAS No.: 14098-24-9
Synonyms: B18C6
Cat. No.: HY-W073183
CAS No.: 14174-09-5
Cat. No.: HY-W004588
CAS No.: 72914-19-3
tBu2bpy is a bidentate nitrogen ligand that coordinates with Pt (II) and Pt (IV) to form functional complexes. The tBu2bpy Pt (II) bis-crown ether complex selectively recognizes Mg 2+ and Zn 2+; both ions significantly enhance the fluorescence of the complex and cause a blue shift of the absorption peak. Its six-coordinate Pt (IV) complex [Pt (X)2Me2 ( tBu2bpy)] inhibits the proliferation of tumor cells. tBu2bpy Pt (IV) complexes bind to DNA through multiple interactions including partial intercalation, groove binding, and electrostatic interaction, and can competitively displace ethidium bromide and covalently bind to purine nucleotides. tBu2bpy can be used in relevant research in fields such as organic synthesis .
Cat. No.: HY-W067376
CAS No.: 303180-11-2
Synonyms: Pyrazole-3,5-dicarboxylic acid monohydrate
Target:
Research Areas:
1H-pyrazole-3,5-dicarboxylic acid hydrate (Pyrazole-3,5-dicarboxylic acid monohydrate) serves as a precursor for the synthesis of 26-membered diazatetraester crown ethers and 39-membered triazahexaester crown ethers containing pyrazole units. 1H-pyrazole-3,5-dicarboxylic acid hydrate acts as a V-type heterocyclic polycarboxylic acid bridging ligand for the construction of Lanthanide III coordination polymers and metal-organic frameworks (MOF) .
Cat. No.: HY-L041
461 compounds
Macrocycles, molecules containing 12-membered or larger rings, are receiving increased attention in small-molecule drug discovery. The reasons are several, including providing access to novel chemical space, challenging new protein targets, showing favorable ADME- and PK-properties. Macrocycles have demonstrated repeated success when addressing targets that have proved to be highly challenging for standard small-molecule drug discovery, especially in modulating macromolecular processes such as protein–protein interactions (PPI). Otherwise, the size and complexity of macrocyclic compounds make possible to ensure numerous and spatially distributed binding interactions, thereby increasing both binding affinity and selectivity.
MCE offers a unique collection of 461 macrocyclic compounds which can be used for drug discovery for high throughput screening (HTS) and high content screening (HCS). MCE Macrocyclic Compound Library is a useful tool for discovering new drugs, especially for “undruggable” targets and protein–protein interactions.
Cat. No.: HY-W007656R
CAS No.: 294-90-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
