Dicyclohexano-18-crown-6-ether
Based on 1 Customer Validation
Dicyclohexano-18-crown-6-ether (DCH18C6) is an excellent strontium chelating agent. Dicyclohexano-18-crown-6-ether exhibits favorable extraction capacity and selectivity toward Sr (II). After chemical modification, Dicyclohexano-18-crown-6-ether is covalently bonded to an organosilicon matrix via co-condensation. DCH18C6-functionalized organosilicon materials are expected to be applied to the extraction and separation of strontium from radioactive waste liquid.
For research use only. We do not sell to patients.
- Purity: 99.58%
- CAS No.: 16069-36-6
- Formula: C20H36O6
- Molecular Weight:372.50
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
25 μM
Compound: 2
|
Antiproliferative activity against HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against HeLa cells after 72 hrs by MTT assay
|
[PMID: 17300184] |
| MCF7 | IC50 |
36 μM
Compound: 2
|
Antiproliferative activity against MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against MCF7 cells after 72 hrs by MTT assay
|
[PMID: 17300184] |
| MIA PaCa-2 | IC50 |
16 μM
Compound: 2
|
Antiproliferative activity against MiaPaCa2 cells after 72 hrs by MTT assay
Antiproliferative activity against MiaPaCa2 cells after 72 hrs by MTT assay
|
[PMID: 17300184] |
| NCI-H460 | IC50 |
16 μM
Compound: 2
|
Antiproliferative activity against H460 cells after 72 hrs by MTT assay
Antiproliferative activity against H460 cells after 72 hrs by MTT assay
|
[PMID: 17300184] |
| SW-620 | IC50 |
7 μM
Compound: 2
|
Antiproliferative activity against SW620 cells after 72 hrs by MTT assay
Antiproliferative activity against SW620 cells after 72 hrs by MTT assay
|
[PMID: 17300184] |
Dicyclohexano-18-crown-6-ether exhibits excellent extraction capacity and selectivity for Sr (II). After chemical modification, it is covalently bonded to an organosilicon matrix via co-condensation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 16069-36-6
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Appearance Solid
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Molecular Weight 372.50
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Formula C20H36O6
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Color White to off-white
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SMILES
C12OCCOCCOC(CCCC3)C3OCCOCCOC1CCCC2
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Synonyms
DCH18C6; Perhydrodibenzo-18-crown-6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (268.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6846 mL | 13.4228 mL | 26.8456 mL | 67.1141 mL |
| 5 mM | 0.5369 mL | 2.6846 mL | 5.3691 mL | 13.4228 mL | |
| 10 mM | 0.2685 mL | 1.3423 mL | 2.6846 mL | 6.7114 mL | |
| 15 mM | 0.1790 mL | 0.8949 mL | 1.7897 mL | 4.4743 mL | |
| 20 mM | 0.1342 mL | 0.6711 mL | 1.3423 mL | 3.3557 mL | |
| 25 mM | 0.1074 mL | 0.5369 mL | 1.0738 mL | 2.6846 mL | |
| 30 mM | 0.0895 mL | 0.4474 mL | 0.8949 mL | 2.2371 mL | |
| 40 mM | 0.0671 mL | 0.3356 mL | 0.6711 mL | 1.6779 mL | |
| 50 mM | 0.0537 mL | 0.2685 mL | 0.5369 mL | 1.3423 mL | |
| 60 mM | 0.0447 mL | 0.2237 mL | 0.4474 mL | 1.1186 mL | |
| 80 mM | 0.0336 mL | 0.1678 mL | 0.3356 mL | 0.8389 mL | |
| 100 mM | 0.0268 mL | 0.1342 mL | 0.2685 mL | 0.6711 mL |