Dibenzo-18-crown-6
Based on 1 Customer Validation
Dibenzo-18-crown-6 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
For research use only. We do not sell to patients.
- CAS No.: 14187-32-7
- Formula: C20H24O6
- Molecular Weight:360.40
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Storage:
RT, sealed storage, away from moisture and light.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
17 μM
Compound: 4
|
Antiproliferative activity against HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against HeLa cells after 72 hrs by MTT assay
|
[PMID: 17300184] |
| MCF7 | IC50 |
49 μM
Compound: 4
|
Antiproliferative activity against MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against MCF7 cells after 72 hrs by MTT assay
|
[PMID: 17300184] |
| MIA PaCa-2 | IC50 |
28 μM
Compound: 4
|
Antiproliferative activity against MiaPaCa2 cells after 72 hrs by MTT assay
Antiproliferative activity against MiaPaCa2 cells after 72 hrs by MTT assay
|
[PMID: 17300184] |
| NCI-H460 | IC50 |
28 μM
Compound: 4
|
Antiproliferative activity against H460 cells after 72 hrs by MTT assay
Antiproliferative activity against H460 cells after 72 hrs by MTT assay
|
[PMID: 17300184] |
| SW-620 | IC50 |
17 μM
Compound: 4
|
Antiproliferative activity against SW620 cells after 72 hrs by MTT assay
Antiproliferative activity against SW620 cells after 72 hrs by MTT assay
|
[PMID: 17300184] |
Chemical Information
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CAS No. 14187-32-7
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Appearance Solid
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Molecular Weight 360.40
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Formula C20H24O6
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Color White to off-white
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SMILES
C12=CC=CC=C1OCCOCCOC3=C(C=CC=C3)OCCOCCO2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, sealed storage, away from moisture and light
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
DMSO : 4 mg/mL (11.10 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (244 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7747 mL | 13.8735 mL | 27.7469 mL | 69.3674 mL |
| 5 mM | 0.5549 mL | 2.7747 mL | 5.5494 mL | 13.8735 mL | |
| 10 mM | 0.2775 mL | 1.3873 mL | 2.7747 mL | 6.9367 mL |