15-Crown-5
Based on 1 Customer Validation
15-Crown-5 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
For research use only. We do not sell to patients.
- Purity: 99.19%
- CAS No.: 33100-27-5
- Formula: C10H20O5
- Molecular Weight:220.26
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
15-Crown-5 is used as an efficient phase transfer catalyst and as a complexing agent. It is used to isolate oxonium ion (H7O3)+ salts especially from a solution of tetrchloroauric acid. It catalyzes the O-alkylation of the sodium salts of Carboxylic acids in the penicillin and cephalosporin series, thereby facilitating esterification reaction without usage of acid. It is also used to facilitate the Williamson synthesis of ethers with hindered alcohols and sodium hydride. It is used with lithium aluminum hydride ide, for performing reduction reactions in hydrogen Solvents. Furthermore, it is involved in the Horner-Wadsworth-Emmons reaction to prepare stilbenes from aldehydes.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 33100-27-5
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Appearance Liquid (Density: 1.324 g/cm³)
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Molecular Weight 220.26
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Formula C10H20O5
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Color Colorless to light yellow
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SMILES
C1COCCOCCOCCOCCO1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 200 mg/mL (908.02 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (252 KB)
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SDS (556 KB)
- English - EN (556 KB)
- Français - FR (556 KB)
- Deutsch - DE (556 KB)
- Norwegian - NO (556 KB)
- Español - ES (556 KB)
- Swedish - SV (556 KB)
- Italian - IT (556 KB)
- Korean - KR (556 KB)
- Portuguese - PT (556 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.5401 mL | 22.7004 mL | 45.4009 mL | 113.5022 mL |
| 5 mM | 0.9080 mL | 4.5401 mL | 9.0802 mL | 22.7004 mL | |
| 10 mM | 0.4540 mL | 2.2700 mL | 4.5401 mL | 11.3502 mL | |
| 15 mM | 0.3027 mL | 1.5134 mL | 3.0267 mL | 7.5668 mL | |
| 20 mM | 0.2270 mL | 1.1350 mL | 2.2700 mL | 5.6751 mL | |
| 25 mM | 0.1816 mL | 0.9080 mL | 1.8160 mL | 4.5401 mL | |
| 30 mM | 0.1513 mL | 0.7567 mL | 1.5134 mL | 3.7834 mL | |
| 40 mM | 0.1135 mL | 0.5675 mL | 1.1350 mL | 2.8376 mL | |
| 50 mM | 0.0908 mL | 0.4540 mL | 0.9080 mL | 2.2700 mL | |
| 60 mM | 0.0757 mL | 0.3783 mL | 0.7567 mL | 1.8917 mL | |
| 80 mM | 0.0568 mL | 0.2838 mL | 0.5675 mL | 1.4188 mL | |
| 100 mM | 0.0454 mL | 0.2270 mL | 0.4540 mL | 1.1350 mL |
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