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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
DDT
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "DDT" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: 2,4′-DDD; o,p'-DDD
Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
2
2 Cited Publications
Synonyms: 4,4'-DDE; p,p'-Dichlorodiphenyldichloroethylene
Research Areas:
p,p'-DDE (4,4'-DDE) is the major and persistent metabolite of DDT. p,p'-DDE is a orally active androgen receptor antagonist with an IC50 of 5 μM and a Ki of 3.5 μM. p,p'-DDE can affect the development and function of the male reproductive system. Additionally, high serum concentrations of p,p'-DDE may be a risk factor for type 2 diabetes in women .
1
1 Cited Publications
Synonyms: 4,4'-DDD; p,p'-Dichlorodiphenyl dichloroethane
Research Areas:
p,p'-DDD (4,4’-DDD) is an organochlorine insecticide, a major metabolite of p,p'-DDT. p,p'-DDD is an agonist at estrogen receptor α(ERα) and ERβ. p,p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p,p'-DDD stimulates cell proliferation in SKBR3 cells. p,p'-DDD activates the AP-1 transcription factor. p,p'-DDD decreases sleep times of barbiturates and steroids in rats .
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Research Areas:
o,p'-DDT (2,4'-DDT) is a chlorinated organic pesticide with estrogenic activity. o,p'-DDT is persistent in the environment, can accumulate in organisms and disrupt the endocrine system. o,p'-DDT is used in agriculture as a pesticide, especially for controlling insect pests. The use of o,p'-DDT has led to toxic effects in organisms, raising widespread concern about its environmental and health effects. o,p'-DDT has also led to research into its long-term effects in ecosystems .
Synonyms: 2,4'-DDE; 2,4-Dichlorodiphenyldichloroethylene; 2,4'-DDE; o,p'-Dichlorodiphenyldichloroethylene
Target:
Research Areas:
o,p'-DDE (2,4-Dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT. It accumulates in smallmouth buffalo, channel catfish, and largemouth bass, and in sediments from DDT manufacturing plants around the Huntsville Spring Branch-Indian Creek tributary system, where it is considered a persistent organic pollutant (POP). o,p'-DDE inhibits estrogen binding to the rainbow trout estrogen receptor (rtER) with an IC50 value of 3.2 μM. It induces concentration-dependent estradiol secretion in co-cultures of granulosa and theca cells isolated from porcine follicles. In ovo exposure to o,p'-DDE increases follicular degeneration and reduces testis size in Japanese medaka (O. latipes).
Cat. No.: HY-B1970S
CAS No.: 221899-88-3
Synonyms: 2,4'-DDT-d8
Cat. No.: HY-B1986S
CAS No.: 93952-19-3
Synonyms: 4,4'-DDE-d8; p,p'-Dichlorodiphenyldichloroethylene-d8
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Research Areas:
Mitotane (Standard) is the analytical standard of Mitotane. This product is intended for research and analytical applications. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
Cat. No.: HY-RS03627
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Research Areas:
DDT Human Pre-designed siRNA Set A contains three designed siRNAs for DDT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Synonyms: 2,4′-DDD-13C6; o,p'-DDD-13C6
Cat. No.: HY-13690S3
CAS No.: 2483736-36-1
Synonyms: 2,4′-DDD-13C12; o,p'-DDD-13C12
Cat. No.: HY-B1984S
CAS No.: 93952-20-6
Synonyms: 4,4'-DDD-d8; p,p'-Dichlorodiphenyl dichloroethane-d8
Cat. No.: HY-W750297
CAS No.: 1571957-95-3
Synonyms: 4,4'-DDD-13C12; p,p'-Dichlorodiphenyl dichloroethane-13C12
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Research Areas:
Chlorfenethol is a dehydrochlorinase inhibitor. Chlorfenethol can be used as a synergist for insecticide DDT to increase its effect on resistant strains .
Cat. No.: HY-159086
CAS No.: 3099108-75-2
Research Areas:
RGB097 is a potent D-dopachrome tautomerase (D-DT) inhibitor with an IC50 value of 0.5 µM. RGB097 has the potential for the research of cancer .
Cat. No.: HY-W753141
CAS No.: 201612-50-2
Synonyms: 4,4'-DDE-13C12; p,p'-Dichlorodiphenyldichloroethylene-13C12
Cat. No.: HY-B1873S
CAS No.: 106031-79-2
Synonyms: DMDT-d6; Methoxcide-d6; Methoxy-DDT-d6
Synonyms: 4,4'-DDE (Standard); p,p'-Dichlorodiphenyldichloroethylene (Standard)
Research Areas:
p,p'-DDE (Standard) is the analytical standard of p,p'-DDE. This product is intended for research and analytical applications. p,p'-DDE (4,4'-DDE) is the major and persistent metabolite of DDT. p,p'-DDE is a orally active androgen receptor antagonist with an IC50 of 5 μM and a Ki of 3.5 μM. p,p'-DDE can affect the development and function of the male reproductive system. Additionally, high serum concentrations of p,p'-DDE may be a risk factor for type 2 diabetes in women .
Cat. No.: HY-13690S2
CAS No.: 2673270-14-7
Synonyms: 2,4′-DDD-d8; o,p'-DDD-d8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
