35 Results for "

Dihydroceramide

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "Dihydroceramide" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P1103
CAS No.: 1030384-98-5
Target:  

CXCR

Research Areas:  

Cancer

CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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Cat. No.: HY-163472
PR280 is a dihydroceramide desaturase 1 (Des1) inhibitor with an IC50 of 700 nM. PR280 is used for the research of metabolic diseases, cancers, and neurodegenerative diseases .
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Cat. No.: HY-141580
CAS No.: 2304-80-5
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

C18 Dihydroceramide is an ester product.
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Cat. No.: HY-135818
CAS No.: 1045857-53-1
Research Areas:  

Cancer

XM462 is a dihydroceramide desaturase inhibitor. XM462 produced a mixed-type inhibition (Ki=2 μM) in vitro. XM462 has dihydroceramide desaturase inhibition both in vitro and in cultured cells with IC50 values of 8.2 and 0.78 μM, respectively. XM462 can be used for the research of tumor .
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Cat. No.: HY-W590669
CAS No.: 5966-29-0
Synonyms: N-Palmitoyl sphinganine; (2S,3R)-2-N-Palmitoyloctadecasphinganine
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

C16-Dihydroceramide (N-Palmitoyl sphinganine) is an ester product.
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Cat. No.: HY-W923646
CAS No.: 352518-80-0
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

C24:1-Dihydro-ceramide is an ester product.
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Cat. No.: HY-W590664
CAS No.: 13031-64-6
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

C2 Dihydroceramide is a derivative of C2 Ceramide (HY-101180). C2 Dihydroceramide enhances the ABCA1-mediated cholesterol efflux to apolipoprotein A-I (apoA-I) without causing cytotoxicity .
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Cat. No.: HY-W590672
CAS No.: 147492-65-7
Research Areas:  

Others

C22 Dihydroceramide is a lipid featuring two saturated hydrophobic tails. Ceramides may be used in developing lipid nanoparticles or liposomes.
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Cat. No.: HY-W590670
CAS No.: 121459-06-1
Synonyms: N-[(2S,3R)-1,3-Dihydroxyoctadecan-2-yl]icosanamide
C20-Dihydroceramide is a biochemical assay reagent.
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Cat. No.: HY-139284
CAS No.: 1246298-60-1
Purity:  ≥99.0%
Synonyms: C24:1 Deoxy Dihydroceramide; C24:1 DeoxyDHceramide; Cer(m18:0/24:1)
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

C24:1 Dihydro 1-deoxyceramide (m18:0/24:1) (C24:1 Deoxy dihydroceramide) is a lipid molecule, which is composed of a long-chain fatty acid (24:1) and a 1-deoxysphingoid backbone. Deoxyceramide accumulates under the conditions of obesity and type 2 diabetes (T2D). Deoxyceramide is unable to be further metabolized to more complex sphingolipid, and is toxic when accumulates in the body. Deoxyceramide increases in differentiated adipocytes in vitro .
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Cat. No.: HY-141580S
CAS No.: 2692624-27-2
C18 Dihydroceramide-d3 is deuterium labeled C18 Dihydroceramide. C18 Dihydroceramide is an ester product .
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Cat. No.: HY-W673679
CAS No.: 649767-83-9
Research Areas:  

Others

(1R,2S)-Deoxy-PR280 is a competitive inhibitor of dihydroceramide desaturase, with a Ki of 6 µM .
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Cat. No.: HY-141580S1
CAS No.: 2699606-99-8
Synonyms: N-octadecaoyl-D-eytho-Dihydosphigosie-d3; Ce(d18:0/18:0)-d3; Ceamide-d3 (d18:0/18:0-d3)
C18 Dihydroceramide-d3-1 (N-octadecaoyl-D-eytho-Dihydosphigosie-d3) is deuterium labeled C18 Dihydroceramide. C18 Dihydroceramide is an ester product .
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Cat. No.: HY-119312
CAS No.: 145774-33-0
Target:  

PKC

Research Areas:  

Cancer

C8 Dihydroceramide is a negative control of C8 Ceramide. C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. C8-Ceramide has anti-proliferation properties and acts as a potent chemotherapeutic agent. C8-Ceramide stimulates dendritic cells to promote T cell responses upon virus infections. C8-Ceramide induces slight activation of protein kinase (PKC) in vitro .
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Cat. No.: HY-P1103A
Target:  

CXCR

Research Areas:  

Cancer

CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Cat. No.: HY-W588183
CAS No.: 61389-70-6
Research Areas:  

Metabolic Disease

C14-Dihydroceramide is an ester product.
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Cat. No.: HY-P11293
CAS No.: 1309855-53-5
Target:  

Melanocortin Receptor

Research Areas:  

Cancer

DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .
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Cat. No.: HY-P4757
CAS No.: 108081-77-2
Target:  

Parasite

Research Areas:  

Others

N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
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Cat. No.: HY-P1321
CAS No.: 158859-98-4
Synonyms: 1229U91; GW1229
Research Areas:  

Neurological Disease

GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
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