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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1012 Results for "
Fc receptor
" in MedChemExpress (MCE) Product Catalog:
Products (1012)
1012 Results for "Fc receptor" in MCE Product Catalog:
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6 Publications Verification
Synonyms: 2,4′-DDD; o,p'-DDD
Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
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6 Publications Verification
Cat. No.: HY-P73388
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; Tumor Necrosis Factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; receptor Activator Of Nuclear Factor Kappa-B Ligand; TRANCE; TNLG6B; RANKL; receptor Activator Of Nuclear Factor Kappa B Ligand; OPGL; Tumor Necrosis Factor Ligand
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5 Cited Publications
Synonyms: P505-15; PRT-2607; BIIB-057
Research Areas:
PRT062607 (P505-15; PRT-2607) is an orally active ATP-competitive Syk inhibitor with an IC50 value of 1 nM, and exhibits at least 80-fold selectivity over other kinases. PRT062607 blocks B cell antigen receptor-mediated activation, Fcε receptor 1-mediated basophil degranulation and microglial phagocytosis, and induces caspase-dependent apoptosis and microglial death. PRT062607 inhibits tumor growth and peripheral nerve injury-induced mechanical allodynia, and prevents neuronal loss. PRT062607 can be used in research related to rheumatoid arthritis, chronic lymphocytic leukemia, non-Hodgkin's lymphoma, neurodegenerative diseases and neuropathic pain .
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Ospemifene (FC-1271a) is an orally active and non-estrogenic selective estrogen receptor modulator (SERM) with Ki values of 380 and 410 nM for estrogen receptor α (ERα) and ERβ, respectively. Ospemifene inhibits caspase-3 activity. Ospemifene inhibits neuronal degeneration, prevents bone loss, and increases vaginal weight and vaginal epithelial height. Ospemifene has anticancer activity against breast cancer .
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2 Cited Publications
Synonyms: HM71224; LY3337641
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Poseltinib (HM71224) is an orally active, selective, irreversible small molecule Bruton tyrosine kinase (BTK) inhibitor. With an IC50 of 1.95 nM. Poseltinib effectively inhibits the signaling mediated by B cell receptors (BCR), Fc receptors (FcR), and Toll-like receptors (TLR). Poseltinib has anti-inflammatory activity and can be used in the research of rheumatoid arthritis .
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2 Cited Publications
Cat. No.: HY-P75553
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RARRES2; HP10433; Retinoic Acid receptor Responder 2; Retinoic Acid receptor Responder (Tazarotene Induced) 2; Chemerin; Tazarotene-Induced Gene 2 Protein; TIG2; RAR-Responsive Protein TIG2; Retinoic Acid receptor Responder Protein 2
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2 Cited Publications
Cat. No.: HY-P72454
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR1; Serine/Threonine-Protein Kinase receptor R4; Prev. ESS1; Activin receptor-Like Kinase 5; Prev. MSSE; TbetaR-I; ALK-5; TGFR-1; ALK5; SKR4; Transforming Growth Factor-Beta receptor Type I; Multiple Self-Healing Squamous Epithelioma; TGF-Beta Recepto
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2 Cited Publications
Cat. No.: HY-P70004
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD36; Leukocyte Differentiation Antigen CD36; CD36 Molecule (CD36 Blood Group); Thrombospondin receptor; Platelet Glycoprotein 4; CD36 Antigen; GPIIIB; PAS-4; GPIV; CD36 Molecule (CD36 Blood Group) Transcript; GP3B; Scavenger receptor Class B, Member 3; F
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1 Cited Publications
Cat. No.: HY-P99381
CAS No.: 1221901-33-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
