6 Results for "

Fosmidomycin

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Fosmidomycin" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-112853
CAS No.: 66508-37-0
Purity:  99.72%
Synonyms: FR-31564
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria.
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Cat. No.: HY-134914
CAS No.: 66508-53-0
Fosmidomycin is an orally active antibiotic, which exhibits antimalarial activity through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DOXP reductoisomerase). Fosmidomycin inhibits P. falciparum strains 3D7, HB3, Dd2 and A2, with IC50s of 150, 71, 170 and 150 ng/mL, respectively. Fosmidomycin exhibits synergistic effect with Clindamycin (HY-B1455), and ameliorates malaria in mouse model .
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Cat. No.: HY-122817
CAS No.: 73226-73-0
Target:  

Antibiotic Parasite

Research Areas:  

Infection

FR900098 sodium is an antimalarial agent that inhibits 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase. FR900098 sodium has no significant acute toxicity or genotoxicity, and does not have the ability to cause chromosome breakage or heterogeneity. FR900098 sodium has no effect on bone marrow red blood cells in NMRI mice .
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Cat. No.: HY-151965
CAS No.: 3037689-82-7
Target:  

Parasite

Research Areas:  

Infection

Antimalarial agent 18 is an potent antimalarial agent, based on electronic, highly lipophilic and siderophoric properties. Antimalarial agent 18 belongs to acyloxymethyl series, as a fosmidomycin surrogate, which is potent IspC inhibitor against the non-mevalonate isoprenoid biosynthesis pathway. Antimalarial agent 18 inhibits P. falciparum (IC50=50 nM) and A. baumanii (IC50=390 nM) .
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Cat. No.: HY-158335
Target:  

Parasite

Research Areas:  

Infection

DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-ketose 5-phosphate reductoisomerase (DXR). DXR-IN-1 is highly selective for P. falciparum DXR (IC50=0.030 μM). DXR-IN-1 inhibits the growth of P. falciparum by binding to the active site of DXR and blocking its catalytic activity .
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Cat. No.: HY-W795264
CAS No.: 66508-32-5
Target:  

Parasite

Research Areas:  

Infection

FR900098 is an antimalarial agent that inhibits 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase. FR900098 has no significant acute toxicity or genotoxicity, and does not have the ability to cause chromosome breakage or heterogeneity. FR900098 has no effect on bone marrow red blood cells in NMRI mice .
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