73226-73-0
73226-73-0
Chemical Structure
FR900098 sodium
- CAS No.: 73226-73-0
- Formula:C5H11NNaO5P
- Molecular Weight:219.11
IUPAC Name: sodium hydrogen (3-(N-hydroxyacetamido)propyl)phosphonate
InChIKey: LCFXFDGYDKNWMD-UHFFFAOYSA-M
SMILES: O=C(C)N(CCCP(O)(O[Na])=O)O
Biological Activity: FR900098 sodium is an antimalarial agent that inhibits 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase. FR900098 sodium has no significant acute toxicity or genotoxicity, and does not have the ability to cause chromosome breakage or heterogeneity. FR900098 sodium has no effect on bone marrow red blood cells in NMRI mice[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FR900098 sodium | 99.77% | FR900098 sodium is an antimalarial agent that inhibits 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase. FR900098 sodium has no significant acute toxicity or genotoxicity, and does not have the ability to cause chromosome breakage or heterogeneity. FR900098 sodium has no effect on bone marrow red blood cells in NMRI mice. | ||||||||||||||||||||
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References
- [1]. Okuhara M, et al. Studies on new phosphonic acid antibiotics. I. FR-900098, isolation and characterization. J Antibiot (Tokyo). 1980 Jan;33(1):13-7. [Content Brief]
- [2]. Wiesner J, et al. FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity. Virulence. 2016 Aug 17;7(6):718-28. [Content Brief]
Keywords
