DXR-IN-1
DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-ketose 5-phosphate reductoisomerase (DXR). DXR-IN-1 is highly selective for P. falciparum DXR (IC50=0.030 μM). DXR-IN-1 inhibits the growth of P. falciparum by binding to the active site of DXR and blocking its catalytic activity.
For research use only. We do not sell to patients.
- Formula: C19H24NO5P
- Molecular Weight:377.37
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Parasite Isoforms
More
Biological Activity
DXR-IN-1 inhibits DXR with IC50=0.035 μM (E. coll), 3.0 μM (M. tuberculosis), respectively[1].
DXR-IN-1 anti-Plasmodium activity is IC50=0.55 μM (Pf3D7), 0.94 μM (PfDd2), respectively[1].
DXR-IN-1 cytotoxicity is IC50=>1000 μM (HepG-2)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 377.37
-
Formula C19H24NO5P
-
SMILES
ON(C(CCC(C1=CC=CC=C1)P(O)(O)=O)=O)CCCC2=CC=CC=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DXR-IN-1 Related Classifications
HY-158335 Related Classifications
Powered by Bioz