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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
GADD45
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "GADD45" in MCE Product Catalog:
1
1 Cited Publications
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1 Cited Publications
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P53R3 is a potent p53 reactivator and restores sequence-specific DNA binding of p53 hot spot mutants, including p53 R175H, p53 R248W and p53 R273H. P53R3 induces p53-dependent antiproliferative effects with much higher specificity than PRIMA-1. P53R3 enhances the recruitment of wild-type p53 and p53 M237I to several target gene promoters. P53R3 strongly enhances the mRNA, total protein and cell surface expression of the death receptor death receptor 5 (DR5). P53R3 is used for cancer research .
Cat. No.: HY-RS05229
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GADD45A Human Pre-designed siRNA Set A contains three designed siRNAs for GADD45A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-179129
CAS No.: 3076960-67-0
AKT-100 is a p53 reactivation agent. AKT-100 significantly inhibits the proliferation of various ovarian and endometrial cancer cells at low concentrations. AKT-100 can upregulate cell cycle regulatory genes (such as p21, GADD45) and pro apoptotic genes (such as NOXA, DR5), and inhibit DNA repair pathways. AKT-100 is commonly used in cancer research .
Cat. No.: HY-RS17861
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Gadd45a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gadd45a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-126311
CAS No.: 331443-00-6
Synonyms: 3,4,5,4'-Tetrahydroxystibene
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4-Hydroxyresveratrol (3,4,5,4'-Tetrahydroxystibene), a Resveratrol (HY-16561) analog, differentially induces pro-apoptotic p53/Bax gene expression. 4-Hydroxyresveratrol induces apoptosis in SV40 virally transformed WI38 cells (WI38VA) cells, but not in WI38 cells. 4-Hydroxyresveratrol significantly induces the expression of p53, GADD45 and Bax genes and concomitantly suppresses the expression of bcl-2 gene in WI38VA .
Cat. No.: HY-RS05230
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GADD45B Human Pre-designed siRNA Set A contains three designed siRNAs for GADD45B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05231
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GADD45G Human Pre-designed siRNA Set A contains three designed siRNAs for GADD45G gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18014
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Gadd45b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gadd45b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26335
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Gadd45g Rat Pre-designed siRNA Set A contains three designed siRNAs for Gadd45g gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24330
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Gadd45a Rat Pre-designed siRNA Set A contains three designed siRNAs for Gadd45a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P70326
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GADD45A; Growth Arrest And DNA-Damage-Inducible 45 Alpha; Prev. DDIT1; DDIT-1; GADD45; Growth Arrest And DNA-Damage-Inducible, Alpha; Growth Arrest And DNA Damage-Inducible Protein GADD45 Alpha; DNA Damage-Inducible Transcript-1; Growth Arrest And DNA Dam
Cat. No.: HY-P85606
Synonyms: DDIT 1; DDIT-1; DDIT1; DNA damage inducible transcript 1; DNA damage-inducible transcript 1 protein; GA45A_HUMAN; GADD45; GADD45A; Growth arrest and DNA damage inducible 45 alpha; Growth arrest and DNA damage inducible alpha; Growth arrest and DNA damage-inducible protein GADD45 alpha.
Cat. No.: HY-RS19838
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Gadd45g Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gadd45g gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24487
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Gadd45b Rat Pre-designed siRNA Set A contains three designed siRNAs for Gadd45b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P70212
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GADD45B; Growth Arrest And DNA-Damage-Inducible Beta; Prev. MYD118; DKFZP566B133; GADD45BETA; Growth Arrest And DNA-Damage-Inducible, Beta; Growth Arrest And DNA Damage-Inducible Protein GADD45 Beta; Myeloid Differentiation Primary Response; Myeloid Diffe
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
