1 Result for "

GW280264X

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GW280264X" in MCE Product Catalog:

9
9 Cited Publications
Cat. No.: HY-115670
CAS No.: 866924-39-2
Purity:  99.30%
Target:  

MMP

Research Areas:  

Inflammation/Immunology Cancer

GW280264X is the mixed ADAM10/TACE (ADAM17) metalloproteinases inhibitor. GW280264X potently blocks TACE (ADAM17) and ADAM10 with IC50s of 8.0 nM and 11.5 nM, respectively . ADAM10 and 17 modulate the immunogenicity of glioblastoma-initiating cells .
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