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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Galantamine
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Galantamine" in MCE Product Catalog:
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15
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Synonyms: GLN-1062
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Benzgalantamine (GLN-1062) is a pro-agent of galantamine, used for the treatment for Alzheimer’s disease.
Cat. No.: HY-76299S
CAS No.: 1128109-00-1
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Cat. No.: HY-76299S2
CAS No.: 2012598-44-4
Synonyms: Galantamine-d3 hydrochloride
Cat. No.: HY-W856819
CAS No.: 469-22-7
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Eseroline is a potent μ-opioid receptor agonist, which is the hydrolytic metabolite of Physostigmine (HY-N6608). Eseroline is a selective and competitive acetylcholinesterase (AChE) inhibitor, with its Ki values for AChE and BuChE being 0.1 μM and 200 μM respectively. Eseroline has nicotinic acetylcholine receptor allosteric enhancing ligand (nAChR-APL) activity, meaning it does not activate the receptor but significantly enhances the signal transduction of Ach triggered by the receptor. Eseroline is neurotoxic, causing cell membrane damage (LDH leakage) and energy metabolism collapse (ATP depletion). Eseroline can be used for the study of Alzheimer's disease .
Cat. No.: HY-A0009S
Synonyms: Galantamine-d3 hydrobromide
Cat. No.: HY-156188
CAS No.: 3038811-77-4
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AChE-IN-41 (Compound 2) is a compound of the Galantamine Memantine hybrid. AChE-IN-41 has the inhibition ability of cholinesterase. AChE-IN-41 shows higher plasma stability and comparable microsomal stability in vitro, while showing lower half-life and faster clearance in vivo .
Cat. No.: HY-101710R
CAS No.: 224169-27-1
Synonyms: GLN-1062 (Standard)
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Research Areas:
Benzgalantamine (Standard) (GLN-1062 (Standard)) is the analytical standard of Benzgalantamine (HY-101710). This product is intended for research and analytical applications. Benzgalantamine (GLN-1062) is a pro-agent of galantamine, used for the treatment for Alzheimer’s disease.
Cat. No.: HY-185199
CAS No.: 216986-48-0
Synonyms: N-Demethylnarwedine
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Nornarwedine (N-Demethylnarwedine) is an amaryllidaceae alkaloid and also a key precursor in the synthetic pathway of Galanthaminone (HY-I0020). Nornarwedine can be synthesized in yeast with 4'-O-methylnorbelladine as the substrate via the catalytic activity of CYP96T6. Nornarwedine is applicable to research related to Alzheimer's disease .
Cat. No.: HY-L236
19,886 compounds
Fragment-based drug discovery (FBDD) offers a strategic advantage by categorizing fragment hits according to their functional groups. This approach facilitates both the further optimization of these hits and the rational design of larger compounds through fragment combination. The amine functional group plays a vital role in drug development, as evidenced by its presence in many marketed drugs like Galantamine, Tacrine, and Rivastigmine. It is instrumental in enhancing solubility, improving bioavailability, and ensuring shelf-life stability—all critical factors for drug efficacy.
MCE offers a collection of 19,886 amine fragments for drug discovery. All of these compounds adhere to the Rule of Three (RO3) criteria for drug-likeness, which MCE offers a collection of 19,886 amine fragments for drug discovery, all of which stipulates a molecular weight ≤ 300 Da, ≤ 3 hydrogen bond donors, ≤ 3 hydrogen bond acceptors, and a cLogP ≤ 3.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
