18 Results for "

Gingerols

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "Gingerols" in MCE Product Catalog:

14
[6]-Gingerol
[6]-Gingerol
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14 Publications Verification
Cat. No.: HY-14615
CAS No.: 23513-14-6
Purity:  99.68%
Synonyms: (S)-(+)-[6]Gingerol
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Disease Research Fields Cancer Zingiberaceae

Target:  

AMPK Apoptosis

[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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5
8-Gingerol
8-Gingerol
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5 Cited Publications
Cat. No.: HY-N0447
CAS No.: 23513-08-8
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Disease Research Fields Inflammation/Immunology Cancer Zingiberaceae

Target:  

TRP Channel Bacterial Apoptosis Autophagy STAT PERK EGFR PI3K Akt mTOR Caspase MMP

8-Gingerol can be found in the rhizome of ginger (Z. officinale) and has oral bioactivity. It activates TRPV1, with an EC50 value of 5.0 µM. 8-Gingerol inhibits COX-2 and also suppresses the growth of H. pylori in vitro. Additionally, 8-Gingerol exhibits anticancer, antioxidant, and anti-inflammatory properties by inhibiting the epidermal growth factor receptor (EGFR) and modulating its downstream STAT3/ERK pathway to suppress the proliferation, migration, and invasion of colorectal cancer cells. 8-Gingerol also exerts immunosuppressive effects by inhibiting oxidative stress, inducing cell cycle arrest, promoting apoptosis, and regulating autophagy. Furthermore, 8-Gingerol has cardioprotective effects. 8-Gingerol is promising for research in the fields of cancer, infection, immunosuppression, and cardiovascular diseases.
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4
10-Gingerol
10-Gingerol
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4 Cited Publications
Cat. No.: HY-N0448
CAS No.: 23513-15-7
Category:  

Zingiber officinale Roscoe Monophenols Ketones, Aldehydes, Acids Phenols Plants Disease Research Fields Inflammation/Immunology Zingiberaceae

Target:  

Free Radical Scavengers AMPK Reactive Oxygen Species (ROS) Akt PI3K Interleukin Related TNF Receptor Apoptosis

10-Gingerol is an AMPK agonist, which is found in the ginger oleoresin from fresh rhizome with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. 10-Gingerol exhibits substantial scavenging activities with an IC50 value of 10.47 μM against DPPH radical, an IC50 value of 1.68 μM against superoxide radical and an IC50 value of 1.35 μM against hydroxyl radical. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM. 10-Gingerol suppresses the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol can be used in research on various common cancers such as ovarian cancer and colon cancer, as well as colitis and neurodegenerative diseases .
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1
[6]-Gingerol (Standard)
[6]-Gingerol (Standard)
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1 Cited Publications
Cat. No.: HY-14615R
CAS No.: 23513-14-6
Synonyms: (S)-(+)-[6]Gingerol (Standard)
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Zingiberaceae

Target:  

Reference Standards AMPK Apoptosis

[6]-Gingerol (Standard) is the analytical standard of [6]-Gingerol. This product is intended for research and analytical applications. [6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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1
Diacetoxy-6-gingerdiol
Diacetoxy-6-gingerdiol
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1 Cited Publications
Cat. No.: HY-133865
CAS No.: 143615-75-2
Purity:  98.01%
Category:  

Zingiber officinale Roscoe Monophenols Other Diseases Phenols Plants Disease Research Fields Zingiberaceae

Target:  

Interleukin Related

Diacetoxy-6-gingerdiol is a gingerol isolated with anti-inflammatory and antioxidant effects, which is found in the dichloromethane extract of rhizomes of ginger (Zingiber officinale Roscoe). Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway .
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10-Gingerol (Standard)
10-Gingerol (Standard)
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Cat. No.: HY-N0448R
CAS No.: 23513-15-7
Category:  

Zingiber officinale Roscoe Natural Products Monophenols Phenols Plants Zingiberaceae

Target:  

Reference Standards AMPK TNF Receptor Apoptosis Akt PI3K Reactive Oxygen Species (ROS) Interleukin Related

10-Gingerol (Standard) is the analytical standard of 10-Gingerol (HY-N0448). This product is intended for research and analytical applications. 10-Gingerol is an AMPK agonist, which is found in the ginger oleoresin from fresh rhizome with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. 10-Gingerol exhibits substantial scavenging activities with an IC50 value of 10.47 μM against DPPH radical, an IC50 value of 1.68 μM against superoxide radical and an IC50 value of 1.35 μM against hydroxyl radical. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM. 10-Gingerol suppresses the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol is promising for research of ulcerative colitis .
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Methyl-6-gingerol
Methyl-6-gingerol
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Cat. No.: HY-N9947
CAS No.: 23513-10-2
Category:  

Natural Products Aframomum melegueta K.Schum. Plants Zingiberaceae

Target:  

Bacterial Antibiotic

Methyl-6-gingerol is an antimicrobial agent derived from Aframomum melegueta that exhibits anti-mycobacterial activity by inhibiting the efflux of toxins within Mycobacterium species .
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(Rac)-8-Gingerol
(Rac)-8-Gingerol
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Cat. No.: HY-N16557
CAS No.: 77398-92-6
Category:  

Natural Products Phenols Plants Zingiberaceae

Target:  

Apoptosis EGFR STAT PERK

(Rac)-8-Gingerol is a non-volatile component. (Rac)-8-Gingerol can be extracted from ginger. (Rac)-8-Gingerol enhances Apoptosis. (Rac)-8-Gingerol decreases the level of phosphorylated EGFR and, accordingly, the phosphorylation levels of its downstream effectors, STAT3 and ERK. (Rac)-8-Gingerol exhibits anticancer activity against colorectal cancer .
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8-Gingerol (Standard)
8-Gingerol (Standard)
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Cat. No.: HY-N0447R
CAS No.: 23513-08-8
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Zingiberaceae

Target:  

Reference Standards TRP Channel Bacterial

8-Gingerol (Standard) is the analytical standard of 8-Gingerol. This product is intended for research and analytical applications. 8-Gingerol, found in the rhizomes of ginger (Z. officinale) with oral bioavailability, activates TRPV1, with an EC50 of 5.0 μM. 8-Gingerol inhibits COX-2, and inhibits the growth of H. pylori in vitro .
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(rac)-Methyl-6-gingerol
(rac)-Methyl-6-gingerol
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Cat. No.: HY-N9947A
CAS No.: 61914-52-1
Category:  

Zingiber officinale Roscoe Natural Products Plants Zingiberaceae

Target:  

Antibiotic Bacterial

(rac)-Methyl-6-gingerol (Compound 14) is the racemate of Methyl-6-gingerol (HY-N9947). Methyl-6-gingerol is an antibiotic that can be isolated from Aframomum melegueta. Methyl-6-gingerol exhibits anti-mycobacterial activity by inhibiting the efflux of toxins within Mycobacterium species .
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5-​Ethoxy-​10-​Gingerol
5-​Ethoxy-​10-​Gingerol
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Cat. No.: HY-N4303
CAS No.: 121771-98-0
Target:  

Drug Derivative

Research Areas:  

Others

5-​Ethoxy-​10-​Gingerol is a derivate of gingerol.
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Methyl-8-gingerol
Methyl-8-gingerol
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Cat. No.: HY-N15732
CAS No.: 503843-60-5
Category:  

Zingiber officinale Roscoe Natural Products Plants Zingiberaceae

Target:  

Others

Methyl-8-gingerol is a compound that can be isolated from ginger .
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6-Dehydro-10-gingerol
6-Dehydro-10-gingerol
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Cat. No.: HY-N15734
CAS No.: 1345675-46-8
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Zingiberaceae

Target:  

Parasite

6-Dehydro-10-gingerol is an antiparasitic compound that can be isolated from ginger roots .
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(Rac)-[6]-Gingerol-13C,d3
(Rac)-[6]-Gingerol-13C,d3
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Cat. No.: HY-100187S
Synonyms: (±)-[6]-Gingerol-13C,d3
(Rac)-[6]-Gingerol- 13C,d3 ((±)-[6]-Gingerol- 13C,d3) is the deuterium and 13C-labeled (Rac)-[6]-Gingerol (HY-100187). (Rac)-[6]-Gingerol is a natural product. (Rac)-[6]-Gingerol can be isolated from rhizomes of Z. officinale. (Rac)-[6]-Gingerol shows moderate anticancer activity against lung cancer, ovarian cancer, melanoma, and colon cancer .
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(Rac)-[6]-Gingerol
(Rac)-[6]-Gingerol
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Cat. No.: HY-100187
CAS No.: 39886-76-5
Synonyms: (±)-[6]-Gingerol
Target:  

Drug Isomer

Research Areas:  

Cancer

(Rac)-[6]-Gingerol is a natural product. (Rac)-[6]-Gingerol can be isolated from rhizomes of Z. officinale. (Rac)-[6]-Gingerol shows moderate anticancer activity against lung cancer, ovarian cancer, melanoma, and colon cancer .
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(±)-10-Gingerol
(±)-10-Gingerol
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Cat. No.: HY-N0448A
CAS No.: 107257-18-1
Category:  

Zingiber officinale Roscoe Other Phenylpropanoids Phenylpropanoids Plants Zingiberaceae

Target:  

AMPK TNF Receptor Apoptosis Akt PI3K Reactive Oxygen Species (ROS) Interleukin Related Free Radical Scavengers

(±)-10-Gingerol is the racemic form of 10-Gingerol (HY-N0448). 10-Gingerol is an AMPK agonist, which is found in the ginger oleoresin from fresh rhizome with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. 10-Gingerol exhibits substantial scavenging activities with an IC50 value of 10.47 μM against DPPH radical, an IC50 value of 1.68 μM against superoxide radical and an IC50 value of 1.35 μM against hydroxyl radical. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM. 10-Gingerol suppresses the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol can be used in research on various common cancers such as ovarian cancer and colon cancer, as well as colitis and neurodegenerative diseases .
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4-Gingerol
4-Gingerol
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Cat. No.: HY-N16862
CAS No.: 41743-68-4
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Zingiberaceae

Target:  

Drug Derivative

4-Gingerol is a natural phenolic compound.
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5-Methoxy-[8]-gingerol
5-Methoxy-[8]-gingerol
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Cat. No.: HY-N15733
CAS No.: 863780-81-8
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Zingiberaceae

Target:  

Others

5-Methoxy-[8]-gingerol is a compound that can be isolated from ginger (Zingiber officinale) .
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