143615-75-2
Chemical Structure
Diacetoxy-6-gingerdiol
- CAS No.: 143615-75-2
- Formula:C21H32O6
- Molecular Weight:380.48
IUPAC Name: (3R,5S)-1-(4-hydroxy-3-methoxyphenyl)decane-3,5-diyl diacetate
InChIKey: PXBFKEHWQRAQQD-RBUKOAKNSA-N
SMILES: CCCCC[C@H](OC(C)=O)C[C@H](OC(C)=O)CCC1=CC=C(O)C(OC)=C1
Biological Activity: Diacetoxy-6-gingerdiol is a gingerol isolated with anti-inflammatory and antioxidant effects, which is found in the dichloromethane extract of rhizomes of ginger (Zingiber officinale Roscoe). Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway[1][2][3].
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Diacetoxy-6-gingerdiol | 99.81% | Diacetoxy-6-gingerdiol is a gingerol isolated with anti-inflammatory and antioxidant effects, which is found in the dichloromethane extract of rhizomes of ginger (Zingiber officinale Roscoe). Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway. | ||||||||||||||||||||
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- [1]. HiroeKikuzaki, et al. Gingerdiol related compounds from the rhizomes of Zingiber officinale. Phytochemistry. Volume 31, Issue 5, 1 May 1992, Pages 1783-1786.
- [2]. Xi H, et al. Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway. Heliyon. 2024 Sep 18;10(21):e37877. [Content Brief]
- [3]. Asamenew G, et al. Characterization of phenolic compounds from normal ginger (Zingiber officinale Rosc.) and black ginger (Kaempferia parviflora Wall.) using UPLC–DAD–QToF–MS[J]. European Food Research and Technology, 2019, 245: 653-665.
Keywords
