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Cat. No.: HY-185554

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HDAC-IN-102

HDAC-IN-102 (Compound 21) is a histone deacetylase (HDAC) inhibitor with an IC₅₀ of 58 μM. HDAC-IN-102 inhibits total HDAC activity and exhibits partial subtype selectivity, with the R-isomer targeting HDAC2 and the S-isomer targeting HDAC8. HDAC-IN-102 exerts antioxidant effects by scavenging DPPH free radicals. HDAC-IN-102 can be used in cancer-related research.

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CAS No.: 626200-64-4
화학식: C₁₈H₂₈O₄
분자량:308.41

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

HDAC-IN-102 Chemical Structure

CAS No.: 626200-64-4

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

All HDAC Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	100 μM Compound: D5	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by WST1 assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by WST1 assay	[PMID: 28065501]

In Vitro

HDAC-IN-102 (1-100 μM; 5-15 min) inhibits total HDAC activity in HeLa nuclear extracts, with an IC₅₀ of 58 μM^[1].
HDAC-IN-102 (30 min) acts as a DPPH free radical scavenger with an IC₅₀ value of 48 μM, and exhibits antioxidant activity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 626200-64-4
분자량 308.41
화학식 C₁₈H₂₈O₄
SMILES

O=C(CC(CCCCC)OC)CCC1=CC=C(C(OC)=C1)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Kumboonma P, et al. Identification of phenolic compounds from Zingiber offinale and their derivatives as histone deacetylase inhibitors and antioxidants[J]. Medicinal Chemistry Research, 2017, 26(3): 650-661.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References

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HDAC-IN-102

All HDAC Isoforms