2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. HDAC-IN-102

HDAC-IN-102 (Compound 21) is a histone deacetylase (HDAC) inhibitor with an IC50 of 58 μM. HDAC-IN-102 inhibits total HDAC activity and exhibits partial subtype selectivity, with the R-isomer targeting HDAC2 and the S-isomer targeting HDAC8. HDAC-IN-102 exerts antioxidant effects by scavenging DPPH free radicals. HDAC-IN-102 can be used in cancer-related research.

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HDAC-IN-102

HDAC-IN-102 Chemical Structure

CAS No. : 626200-64-4

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Other Forms of HDAC-IN-102:

HDAC-IN-102 Related Antibodies

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Description

HDAC-IN-102 (Compound 21) is a histone deacetylase (HDAC) inhibitor with an IC50 of 58 μM. HDAC-IN-102 inhibits total HDAC activity and exhibits partial subtype selectivity, with the R-isomer targeting HDAC2 and the S-isomer targeting HDAC8. HDAC-IN-102 exerts antioxidant effects by scavenging DPPH free radicals. HDAC-IN-102 can be used in cancer-related research[1].

In Vitro

HDAC-IN-102 (1-100 μM; 5-15 min) inhibits total HDAC activity in HeLa nuclear extracts, with an IC50 of 58 μM[1].
HDAC-IN-102 (30 min) acts as a DPPH free radical scavenger with an IC50 value of 48 μM, and exhibits antioxidant activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HDAC-IN-102 Related Antibodies
Molecular Weight

308.41

Formula

C18H28O4
CAS No.
SMILES

O=C(CC(CCCCC)OC)CCC1=CC=C(C(OC)=C1)O
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Room temperature in continental US; may vary elsewhere.
Storage

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Purity & Documentation
References
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HDAC-IN-102 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDAC-IN-102626200-64-4HDACHistone deacetylasesHDAC7HDAC8HDAC4DPPH free radicalHDAC2HeLa nuclear extracthistone deacetylasecancerInhibitorinhibitorinhibit

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