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Cat. No.: HY-185554B

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(R)-HDAC-IN-102

(R)-HDAC-IN-102 is a HDAC2 inhibitor and the isomer of HDAC-IN-102 (HY-185554). HDAC-IN-102 inhibits total HDAC with an IC₅₀ of 58 μM and exhibits partial subtype selectivity. Specifically, (R)-HDAC-IN-102 targets HDAC2, while (S)-HDAC-IN-102 (HY-185554A) targets HDAC8. HDAC-IN-102 exerts antioxidant effects via scavenging DPPH free radicals and can be used in cancer-related research.

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CAS No.: 1177382-00-1
Formule: C₁₈H₂₈O₄
Masse moléculaire:308.41

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Please store the product under the recommended conditions in the Certificate of Analysis.

(R)-HDAC-IN-102 Chemical Structure

CAS No.: 1177382-00-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
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Activité biologique

Description

IC₅₀ & Target

HDAC2

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In Vitro

HDAC-IN-102 (Compound 21; 30 min) scavenges DPPH free radicals with an IC₅₀ value of 48 μM, exhibiting antioxidant activity^[1]。

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1177382-00-1
Masse moléculaire 308.41
Formule C₁₈H₂₈O₄
SMILES

CCCCC[C@@H](OC)CC(CCC1=CC(OC)=C(C=C1)O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Koh EM, et al. Modulation of macrophage functions by compounds isolated from Zingiber officinale. Planta Med. 2009;75(2):148-151. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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(R)-HDAC-IN-102

Voir tous les produits spécifiques à Isoform HDAC