1177382-00-1
Chemical Structure
(R)-HDAC-IN-102
- CAS No.: 1177382-00-1
- Formula:C18H28O4
- Molecular Weight:308.41
InChIKey: FBIPGCRLBUAKTF-MRXNPFEDSA-N
SMILES: CCCCC[C@@H](OC)CC(CCC1=CC(OC)=C(C=C1)O)=O
Biological Activity: (R)-HDAC-IN-102 is a HDAC2 inhibitor and the isomer of HDAC-IN-102 (HY-185554). HDAC-IN-102 inhibits total HDAC with an IC50 of 58 μM and exhibits partial subtype selectivity. Specifically, (R)-HDAC-IN-102 targets HDAC2, while (S)-HDAC-IN-102 (HY-185554A) targets HDAC8. HDAC-IN-102 exerts antioxidant effects via scavenging DPPH free radicals and can be used in cancer-related research[1].
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(R)-HDAC-IN-102 | (R)-HDAC-IN-102 is a HDAC2 inhibitor and the isomer of HDAC-IN-102 (HY-185554). HDAC-IN-102 inhibits total HDAC with an IC50 of 58 μM and exhibits partial subtype selectivity. Specifically, (R)-HDAC-IN-102 targets HDAC2, while (S)-HDAC-IN-102 (HY-185554A) targets HDAC8. HDAC-IN-102 exerts antioxidant effects via scavenging DPPH free radicals and can be used in cancer-related research. | |||||||||||||||||||||
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Keywords