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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Glucocerebrosides
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Glucocerebrosides" in MCE Product Catalog:
13
Target:
Research Areas:
Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM.
13
13 Cited Publications
Synonyms: Genz-112638; Eliglustat tartrate
Target:
Research Areas:
Eliglustat hemitartrate is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM.
Cat. No.: HY-165035
CAS No.: 85305-87-9
Synonyms: Glucocerebrosides; Gaucher cerebroside; GluCers (gaucher's spleen)
Research Areas:
Glucosylceramide (Glucocerebrosides) (gaucher's spleen) is a glycosphingolipid and primary substrate of acid β-glycosidase, suppresses tyrosine phosphorylation of insulin receptor and IRS-1, disrupts insulin signaling cascade and triggers pancreatic β-cell dysfunction. Glucosylceramide (Gaucher's spleen) accumulates in rodents and induces obesity and insulin resistance, restores systemic glucose homeostasis and insulin sensitivity when synthesis is suppressed. Glucosylceramide (Gaucher's spleen) accumulates in the brain of chronic neuronopathic Gaucher disease mice with age and can be applied for research on insulin resistance, type 2 diabetes mellitus and chronic neuronopathic Gaucher disease .
Cat. No.: HY-14885S1
Synonyms: Genz 99067-d4
Cat. No.: HY-14885S
CAS No.: 1884556-84-6
Synonyms: Genz 99067-d15 tartrate
Cat. No.: HY-142105R
CAS No.: 3639-21-2
Synonyms: 2-Ethyl-2-hydroxybutyric acid (Standard)
Cat. No.: HY-14885R
CAS No.: 491833-29-5
Synonyms: Genz 99067 (Standard)
Research Areas:
Eliglustat (Standard) is the analytical standard of Eliglustat. This product is intended for research and analytical applications. Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM.
Cat. No.: HY-14885S2
CAS No.: 1628700-80-0
Synonyms: Genz 99067-d15
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
