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Results for "

HAP 1

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

4

Peptides

5

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P4096
    HAP-1

    		Bacterial Inflammation/Immunology
    HAP-1 is a synovial-targeted transduction peptide. HAP-1 facilitates specific internalization of protein complexes into human and rabbit synovial cells. HAP-1 fused to an antimicrobial peptide, (KLAK)2, to generate a proapoptotic peptide DP2 .
    HAP-1
  • HY-153119
    TMX-4153

    		PROTACs PIKfyve Inflammation/Immunology
    TMX-4153 is a selective PIP4K2C PROTAC degrader. TMX-4153 induces PIP4K2C degradation in MOLT4 cells (DC50 = 24 nM) and HAP1 cells (DC50 = 361 nM). TMX-4153 can be used for the study of biological functions of PIP4K2C (immune modulation)-related diseases. (Pink: BTK ligand (HY-177432), Blue: VHL Ligand (HY-112078), Black: Linker) .
    TMX-4153
  • HY-174866
    BT-O2C

    		Histone Acetyltransferase Epigenetic Reader Domain PROTACs Cancer
    BT-O2C is a highly selective p300 PROTAC degrader. BT-O2C can significantly degrade the level of p300 in HAP1 cells. BT-O2C has significant cytotoxicity in CIC:DUX4 sarcoma (CDS) cell lines (IC50 ranges from 152 to 221 nM) and significantly reduces the expression of CDS target genes (ETV1, ETV4, ETV5). BT-O2C can be used for research on cancer. (Pink: p300 Ligand (HY-174868); Blue: CRBN Ligand (HY-W023573); Black: Linker; CRBN Ligand+Linker (HY-174869)) .
    BT-O2C
  • HY-RS24355
    Hap1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Hap1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hap1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Hap1 Rat Pre-designed siRNA Set A
    Hap1 Rat Pre-designed siRNA Set A
  • HY-RS06000
    HAP1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    HAP1 Human Pre-designed siRNA Set A contains three designed siRNAs for HAP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HAP1 Human Pre-designed siRNA Set A
    HAP1 Human Pre-designed siRNA Set A
  • HY-RS17886
    Hap1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Hap1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hap1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Hap1 Mouse Pre-designed siRNA Set A
    Hap1 Mouse Pre-designed siRNA Set A
  • HY-173281
    MAT2A-IN-24

    		Methionine Adenosyltransferase (MAT) Cancer
    MAT2A-IN-24 (Compound 9) is an inhibitor of methionine adenosyltransferase 2a (MAT2a). The IC50 value for the inhibition of MAT2a is 20 nM, and the IC50 value for the antiproliferative activity against HAP1MTAP–/– cells is 10 nM. MAT2A-IN-24 can be used in the research field of tumor diseases associated with MTAP deficiency .
    MAT2A-IN-24
  • HY-180573
    ART5537

    		Arf Family GTPase Cancer
    ART5537 is a selective EXO1 inhibitor with a IC50 of 3.4 nM and a Kd of 6.8 nM. ART5537 exerts cellular homologous recombination (HR) inhibition with EC50 of 7.2 nM in HAP1 parental cells. ART5537 shows >200-fold selectivity over a panel of the wider nuclease superfamily. ART5537 exerts biological effects that are exclusively driven by EXO1 inhibition. ART5537 demonstrates sensitization to ionizing radiation and synergy with Olaparib (HY-10162). ART5537 can be used for research in breast cancer and colorectal adenocarcinoma .
    ART5537

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