2. Peptides
  3. Peptide and Derivatives
  4. Cys-HAP-1

Cys-HAP-1 is a synovium-homing peptide that specifically binds to human and rabbit fibroblast-like synoviocytes, and does not bind to human umbilical vein endothelial cells regardless of TNF-α treatment. Cys-HAP-1 enables targeted drug delivery to inflamed joints after conjugation with liposomes loaded with anti-arthritic agents. Cys-HAP-1 can be used in studies related to adjuvant arthritis.

For research use only. We do not sell to patients.

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Cys-HAP-1

Cys-HAP-1 Chemical Structure

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Other Forms of Cys-HAP-1:

Cys-HAP-1 Related Antibodies

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Description

Cys-HAP-1 is a synovium-homing peptide that specifically binds to human and rabbit fibroblast-like synoviocytes, and does not bind to human umbilical vein endothelial cells regardless of TNF-α treatment. Cys-HAP-1 enables targeted drug delivery to inflamed joints after conjugation with liposomes loaded with anti-arthritic agents. Cys-HAP-1 can be used in studies related to adjuvant arthritis[1].

Molecular Weight

1438.61

Formula

C63H95N19O18S
Sequence

Cys-Ser-Phe-His-Gln-Phe-Ala-Arg-Ala-Thr-Leu-Ala-Ser
Sequence Shortening

CSFHQFARATLAS
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cys-HAP-1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cys-HAP-1Otherssynoviumanti-arthritic agentsrabbit fibroblast-like synoviocytes (rFLS)fibroblast-like synoviocytesTNF-αhuman fibroblast-like synoviocytes (hFLS)inflamed jointsrat adjuvant-induced arthritis modeladjuvant-induced arthritishuman umbilical vein endothelial cellsInhibitorinhibitorinhibit

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