3055107-34-8
3055107-34-8
Chemical Structure
BT-O2C
- CAS No.: 3055107-34-8
- Formula:C48H48F5N9O8
- Molecular Weight:973.94
InChIKey: PLGWVGZEAXCWGB-HFRVWLGUSA-N
SMILES: O=C(N(CC1=CC=C(F)C=C1)[C@@H](C)C(F)(F)F)CN(C(N[C@]23C[C@@H](F)C4=C3C=CC(C5=CN(CC(NCCCCCCCNC6=CC7=C(C(N(C(CC8)C(NC8=O)=O)C7=O)=O)C=C6)=O)N=C5)=C4)=O)C2=O
Biological Activity: BT-O2C is a p300 PROTAC degrader. BT-O2C induces p300 degradation via proteasome- and ubiquitin-like modification-dependent pathways, downregulates the expression of CIC::DUX4 sarcoma target genes, and exerts cytotoxicity against such sarcoma cells. BT-O2C can be used in CIC::DUX4 sarcoma-related studies[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BT-O2C | 99.31% | BT-O2C is a p300 PROTAC degrader. BT-O2C induces p300 degradation via proteasome- and ubiquitin-like modification-dependent pathways, downregulates the expression of CIC::DUX4 sarcoma target genes, and exerts cytotoxicity against such sarcoma cells. BT-O2C can be used in CIC::DUX4 sarcoma-related studies. | ||||||||||||||||||||
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