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Hex

" in MedChemExpress (MCE) Product Catalog:

50

Inhibitors & Agonists

9

Fluorescent Dyes

6

Biochemical Assay Reagents

3

Peptides

3

Natural
Products

1

Isotope-Labeled Compounds

2

Antibodies

4

Click Chemistry

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131904
    POMHEX
    3 Publications Verification

    Enolase Apoptosis Metabolic Disease Cancer
    POMHEX, a racemic mixture and a cell-permeable pivaloyloxymethyl (POM) proagent of HEX, is a potent, ENO2-specific inhibitor of enolase. POMHEX exhibits low-nanomolar potency against ENO1-deleted cells in vitro and is capable of eradicating ENO1-deleted xenografted tumours in vivo. POMHEX is a potent glycolysis inhibitor .
    POMHEX
  • HY-136205
    IA-Alkyne
    4 Publications Verification

    Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide

    TRP Channel Infection Inflammation/Immunology
    IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    IA-Alkyne
  • HY-131904A

    Enolase Parasite Infection Cancer
    Hex is an enolase inhibitor and antimalarial agent with Ki values of 74.4 nM and 269.4 nM for ENO2 and ENO1, respectively. Hex is a NfENO and TbENO inhibitor with IC50s value of 0.14 μM and 2.1 μM, respectively. Hex has antimalarial activity against Plasmodium falciparum 3D7, Naegleria fowleri trophozoites and Plasmodium berghei ANKA strain. Hex has anti-tumor effects against intracranial tumors .
    Hex
  • HY-W010532

    (E)-Hex-3-enoic acid

    Biochemical Assay Reagents Others
    (E)-Hex-3-enoic acid is an unsaturated organic compound. It is commonly used as a fragrance ingredient in a variety of products, including food, beverages, and personal care products, and it can also be used as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. In addition, (E)-Hex- 3-enoic acid has been investigated for its potential use as a biobased solvent due to its low toxicity and biodegradability, as well as its potential antibacterial and antifungal properties, which may make it useful for developing new Antibacterial agents.
    trans-3-Hexenoic acid
  • HY-Y0925

    Hex-5-ynoic acid

    Drug Intermediate PROTAC Linkers Others
    5-Hexynoic acid (Hex-5-ynoic acid) is an alkynoic acid. 5-Hexynoic acid serves as a drug intermediate for the synthesis of 3-alkoxy-2-cyclohexenone .
    5-Hexynoic acid
  • HY-W015936

    trans-Hex-2-en-1-ol

    Environmental Pollutants Biochemical Assay Reagents Others
    (E)-Hex-2-en-1-ol belongs to the class of unsaturated alcohols consisting of a six-carbon chain with a double bond between carbon atoms 2 and 3 and a hydroxyl group attached to carbon atom 1. The compound has a grassy or herbaceous smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It can also be used as a fragrance ingredient in personal care products and as a starting material for the synthesis of other organic compounds. Furthermore, (E)-hex-2-en-1-ol can be used as a solvent or reagent in various chemical reactions.
    (E)-Hex-2-en-1-ol
  • HY-N2426

    Interleukin Related Inflammation/Immunology
    Clerodendrin is a nature product could be isolated from Lobelia chinensis. Clerodendrin is a potent dual Interleukin-4 (IL-4) inhibitor and β-hexosaminidase (Hex) inhibitor .
    Clerodendrin
  • HY-104050
    M-31850
    2 Publications Verification

    Glycosidase Metabolic Disease
    M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor with IC50s of 6.0 μM and 3.1 μM for human HexA and human HexB, respectively. M-31850 also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM .
    M-31850
  • HY-114289
    6-HEX
    1 Publications Verification

    Fluorescent Dye Others
    6-HEX is one kind of light base group, the wave length is 532 nm, the wave length is 556 nm. 6-HEX can be used to record nucleic acid sequences and design optical materials. 6-HEX can be used to record nucleic acids at 543 nm radiation, and at 550 nm and 650 nm radiation (5 nm radiation), it can be used to directly locate the base of the cell group .
    6-HEX
  • HY-W015943

    5-Hexyn-1-ol

    PROTAC Linkers Cancer
    Hex-5-yn-1-ol (5-Hexyn-1-ol) is a PROTAC linker that can be used in the synthesis of PROTACs.
    Hex-5-yn-1-ol
  • HY-34643

    Hept-6-ynoic acid

    Drug Intermediate Others
    Hexanoylic acid (Hex-6-ynoic acid) is a drug intermediate. Hexanoylic acid can be functionalized by esterification reaction to paclitaxel (HY-B0015), enabling it to undergo an efficient ring addition reaction with β-cyclodextrin, thereby enhancing its water solubility, stability and targeting properties .
    6-Heptynoic acid
  • HY-156586

    ASN90

    OGA Tau Protein Neurological Disease
    Egalognastat (ASN90) is a selective, brain-penetrant and orally active O-GlcNAcase (OGA) enzyme inhibitor with an IC50 value of 10.2 nM. Egalognastat increases O-GlcNAcylation of intracellular proteins like tau and α-synuclein, preventing their aggregation and toxicity. Egalognastat does not inhibit hexosaminidase (Hex). Egalognastat can be used for the research of neurodegenerative diseases, such as tauopathies and α-synucleinopathies (e.g., Alzheimer’s disease and Parkinson’s disease) .
    Egalognastat
  • HY-P3441A

    FAP Cancer
    3BP-4089 TFA is a highly efficient fibroblast activation protein (FAP) targeting peptide. 3BP-4089 TFA is often conjugated with radionuclides for tumor diagnosis and research .
    3BP-4089 TFA
  • HY-W050829

    PROTAC Linkers Cancer
    tert-Butyl hex-5-yn-1-ylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
    tert-Butyl hex-5-yn-1-ylcarbamate
  • HY-W010531

    trans-2-Hexenoic acid

    Biochemical Assay Reagents Others
    trans-Hex-2-enoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    trans-Hex-2-enoic acid
  • HY-161242A

    Bcl-2 Family Cancer
    CBI1 formic is a covalent BAX inhibitor. CBI1 formic selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 formic blocks t-2-hex lipidation and oligomerization of BAX. CBI1 formic inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex .
    CBI1 formic
  • HY-P3441

    FAP Cancer
    3BP-4089 is a highly efficient fibroblast activation protein (FAP) targeting peptide. 3BP-4089 is often conjugated with radionuclides for tumor diagnosis and research .
    3BP-4089
  • HY-D0828

    DNA Stain MOFs Others
    3,6-Dichlorotrimellitic acid is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.
    3,6-Dichlorotrimellitic acid
  • HY-D0829

    DNA Stain Others
    3,6-Dichlorotrimellitic anhydride is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.
    3,6-Dichlorotrimellitic anhydride
  • HY-D1891

    Fluorescent Dye Others
    6-HEX, SE is a derivative of 6-HEX that is widely used in nucleic acid sequencing .
    6-HEX, SE
  • HY-W130918A

    PROTAC Linkers Cancer
    Hex-3-enedinitrile is a PROTAC linker that can be used in the synthesis of PROTACs.
    Hex-3-enedinitrile
  • HY-W453529

    PROTAC Linkers Cancer
    Ethyl hex-5-ynoate is a PROTAC linker that can be used in the synthesis of PROTACs.
    Ethyl hex-5-ynoate
  • HY-W023192

    PROTAC Linkers Cancer
    Hex-5-yn-1-amine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
    Hex-5-yn-1-amine hydrochloride
  • HY-W411604

    PROTAC Linkers Cancer
    tert-Butyl hex-5-ynoate is the linker that can be used for PROTAC synthesis of PROTAC cGAS degrader-1 (HY-172208) .
    tert-Butyl hex-5-ynoate
  • HY-W783829

    Hex-2-trans-enoyl-CoA

    Endogenous Metabolite Metabolic Disease
    (2E)-Hexenoyl-CoA (Hex-2-trans-enoyl-CoA) is an intermediate in fatty acid metabolism. (2E)-Hexenoyl-CoA undergoes reductive carboxylation to yield butylmalonyl-CoA .
    (2E)-Hexenoyl-CoA
  • HY-CE00457

    (Z)-Hex-3-enoyl-coenzyme A

    Biochemical Assay Reagents Metabolic Disease
    (Z)-Hex-3-enoyl-CoA ((Z)-Hex-3-enoyl-coenzyme A) is a fatty acyl-CoA.
    (Z)-Hex-3-enoyl-CoA
  • HY-D1893

    Fluorescent Dye Others
    HEX azide, 6-isomer, a derivate of fluorescent dye hexachlorofluorescein (HEX), can be used for labeling oligonucleotides .
    HEX azide, 6-isomer
  • HY-163011

    Biochemical Assay Reagents Others
    Dicamba-hex-5-ynoic acid is a hapten that can be coupled with Ovalbumin (OVA). Dicamba-hex-5-ynoic acid can be used in dicamba analysis .
    Dicamba-hex-5-ynoic acid
  • HY-164869

    Biochemical Assay Reagents Others
    1-Hex-GlcNAlk is a metabolic chemical reporter (MCR) utilized in glycosylation research. 1-Hex-GlcNAlk exhibits robust labeling over background with negligible amounts of nonspecific chemical labeling in cell lysates .
    1-Hex-GlcNAlk
  • HY-W570685

    PROTAC Linkers Cancer
    Hex-5-yn-1-yl 4-methylbenzenesulfonate is a PROTAC linker that can be used in the synthesis of PROTACs.
    Hex-5-yn-1-yl 4-methylbenzenesulfonate
  • HY-W344269

    PROTAC Linkers Cancer
    Tert-butyl(hex-5-yn-1-yloxy)dimethylsilane is a PROTAC linker that can be used in the synthesis of PROTACs.
    Tert-butyl(hex-5-yn-1-yloxy)dimethylsilane
  • HY-W008836S

    trans-3-Hexen-1-ol-d2

    Isotope-Labeled Compounds Others
    (E)-Hex-3-en-1-ol-d2 is deuterated labeled (E)-Hex-3-en-1-ol.
    (E)-Hex-3-en-1-ol-d2
  • HY-W436499

    Biochemical Assay Reagents Others
    1,5-Anhydro-2-deoxy-D-lyxo-hex-1-enitol tribenzoate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    1,5-Anhydro-2-deoxy-D-lyxo-hex-1-enitol tribenzoate
  • HY-W698362

    Biochemical Assay Reagents Others
    α-D-threo-Hex-2-enopyranoside,methyl 2,3-dideoxy-4,6-diacetate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    α-D-threo-Hex-2-enopyranoside,methyl 2,3-dideoxy-4,6-diacetate
  • HY-161242

    Bcl-2 Family Cancer
    CBI1 is a covalent BAX inhibitor. CBI1 selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 blocks t-2-hex lipidation and oligomerization of BAX. CBI1 inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex .
    CBI1
  • HY-147107

    Insecticide Others
    OfHex1-IN-2 (compound I-79) is a potent β-N-acetylhexosaminidase OfHex1 inhibitor. OfHex1-IN-2 can be used in control of insect .
    OfHex1-IN-2
  • HY-RS06159

    Small Interfering RNA (siRNA) Others

    HHEX Human Pre-designed siRNA Set A contains three designed siRNAs for HHEX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HHEX Human Pre-designed siRNA Set A
    HHEX Human Pre-designed siRNA Set A
  • HY-D2737

    BHQ-2 DMT amidite

    Fluorescent Dye Others
    DMT-BH2 amidite (BHQ-2 DMT amidite) is a black quencher dye for the synthesis of dual-labeled oligonucleotide probes for qPCR bearing 5'-quencher. This quencher is ideal for HEX, JOE, ROX, Cyanine5, and other dyes with emissions in the orange and red parts of the spectrum.
    DMT-BH2 amidite
  • HY-W145544

    1,5-Anhydro-2-deoxy-6-O-(triisopropylsilyl)-D-arabino-Hex-1-enitol

    Biochemical Assay Reagents Others
    6-O-(Triisopropylsilyl)-D-glucal is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    6-O-(Triisopropylsilyl)-D-glucal
  • HY-130510

    Fluorescent Dye Others
    6-HEX dipivaloate is an amino-bindable fluorescent probe that can be used to label peptides and oligonucleotides. 6-HEX dipivaloate is widely used in nucleic acid sequencing and related research .
    6-HEX dipivaloate
  • HY-116295

    P2Y Receptor p38 MAPK Calcium Channel Cardiovascular Disease
    MRS2690 is a selective P2Y14 receptor agonist. MRS2690 inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and mediating concentration-dependent vasoconstriction of porcine coronary arteries. MRS2690 induces intracellular calcium mobilization, activates P38 and stimulates [ 35S]GTPγS binding to RBL-2H3 cell membranes. MRS2690 enhances antigen (NP-BSA)-, C3a-induced β-hexosaminidase (β-Hex) release. MRS2690can be used for ischemic heart disease .
    MRS2690
  • HY-116295A

    P2Y Receptor p38 MAPK Calcium Channel Cardiovascular Disease
    MRS2690 disodium is a selective P2Y14 receptor agonist. MRS2690 disodium inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and mediating concentration-dependent vasoconstriction of porcine coronary arteries. MRS2690 disodium induces intracellular calcium mobilization, activates P38 and stimulates [ 35S]GTPγS binding to RBL-2H3 cell membranes. MRS2690 enhances antigen (NP-BSA)-, C3a-induced β-hexosaminidase (β-Hex) release. MRS2690 disodium can be used for ischemic heart disease .
    MRS2690 disodium
  • HY-W822795

    PROTAC Linkers Cancer
    Benzyl hex-5-yn-1-ylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
    Benzyl hex-5-yn-1-ylcarbamate
  • HY-W840196

    Biochemical Assay Reagents Others
    Hex-5-ynehydrazide is a bifunctional linker reagent with a terminal hydrazide group and a propargyl group. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
    Hex-5-ynehydrazide
  • HY-201158

    5'-Hexynyl phosphoramidite

    Phosphoramidites
    2-Cyanoethyl hex-5-yn-1-yl diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
    2-Cyanoethyl hex-5-yn-1-yl diisopropylphosphoramidite
  • HY-172218

    E3 Ligase Ligand-Linker Conjugates Others
    Lenalidomide-hex-5-ynoic acid is a conjugate of E3 ligase ligand and linker, and can be used to synthesize PROTACs, such as PROTAC cGAS degrader-1 (HY-172208) .
    Lenalidomide-hex-5-ynoic acid
  • HY-D2739

    Fluorescent Dye Others
    SIMA phosphoramidite, 6-isomer is a xanthene dye with spectral characteristics similar to those of HEX but with a higher quantum yield. SIMA has higher stability during deprotection under alkaline conditions.
    SIMA phosphoramidite, 6-isomer
  • HY-108241A

    Glycosidase Neurological Disease
    Galacto-PUGNAc is a selective competitive inhibitor of lysosomal β-hexosaminidases (HEX), with Ki values of 51 and 18 nM, for hHEXA and hHEXB, respectively. Galacto-PUGNAc elevates GM2 ganglioside levels in neuroblastoma cells. Galacto-PUGNAc can be used for the research of neurodegenerative disorders .
    Galacto-PUGNAc
  • HY-P2835A

    Biochemical Assay Reagents Others
    Alginate lyase, Sphingomonas sp. (EC 4.2.2.3) is an enzyme that catalyzes the chemical reaction:Eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. Alginate lyase, Sphingomonas sp. (EC 4.2.2.3) belongs to the family of lyases, participates in fructose and mannose metabolism.
    Alginate lyase, Sphingomonas sp.
  • HY-104050R

    Glycosidase Reference Standards Metabolic Disease
    M-31850 (Standard) is the analytical standard of M-31850 (HY-104050). This product is intended for research and analytical applications. M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor with IC50s of 6.0 μM and 3.1 μM for human HexA and human HexB, respectively. M-31850 also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM .
    M-31850 (Standard)

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