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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
LSD1/2-IN-4
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "LSD1/2-IN-4" in MCE Product Catalog:
Cat. No.: HY-151194
CAS No.: 2821068-09-9
Target:
Research Areas:
LSD1/2-IN-4, a PCPA derivative, is an inhibitor of lysine-specific demethylase 1 (LSD1) and lysine-specific demethylase 2 (LSD2). LSD1/2-IN-4 inhibits LSD1 and LSD2 with Ki values of 0.11 μM and 130 μM, respectively. LSD1/2-IN-4 can be used for the research of several cancers including T-cell acute lymphoblastic leukemia (TALL) .
10
10 Publications Verification
Synonyms: NorcoclaurINe; Demethyl-CoclaurINe
10
10 Publications Verification
Cat. No.: HY-N2037A
CAS No.: 11041-94-4
Synonyms: NorcoclaurINe hydrochloride
Category:
Plants Lindera aggregata (Sims) Kosterm. Alkaloids Phenols Polyphenols Lauraceae Disease Research Fields Isoquinoline Alkaloids Endocrinology Cancer
Target:
6
Phenelzine sulfate, an antidepressant agent, is an irreversible and orally active monoamine oxidase (MAO-A and MAO-B) inhibitor. Phenelzine sulfate inhibits GABA transaminase and primary amine oxidase (PrAO), and sequester reactive aldehydes. Phenelzine sulfate also inhibits LSD1 (Ki: 5.6 μM) and suppresses oxidative stress and lipogenesis. Phenelzine sulfate elevates neurotransmitters (serotonin, norepinephrine, dopamine). Phenelzine sulfate is studied in neurological, metabolic and cancer diseases for depression and anxiety disorders, stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, inflammatory pain, obesity and prostate cancer [2] .
Cat. No.: HY-B1018AS
CAS No.: 1219798-40-9
Synonyms: NorcoclaurINe (Standard); Demethyl-CoclaurINe (Standard)
Cat. No.: HY-151190
CAS No.: 2821068-03-3
Synonyms: S1024
Target:
Research Areas:
cis-4-Br-2,5-F2-PCPA (S1024) is a selective inhibitor of lysine-specific demethylase 1 (LSD1), with a Ki value of 94 nM instead of 8.4 μM for LSD2. There is aberrant expression of LSD1 in cancer stem cells, cis-4-Br-2,5-F2-PCPA inhibits LSD1 cell proliferation and by increasing the level of dimethylated histone H3 at K4 (H3K4) in CCRF-CEM cells .
Cat. No.: HY-17447AS
Synonyms: (1S,2R)-SKF 385-d5 hydrochloride
Cat. No.: HY-N2037AR
CAS No.: 11041-94-4
Synonyms: NorcoclaurINe hydrochloride (Standard)
Cat. No.: HY-N2037AS1
Synonyms: NorcoclaurINe-d4-1 hydrochloride; Demethyl-CoclaurINe-d4-1 hydrochloride
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
