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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
M polyprotein
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "M polyprotein" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: PBI-0451
Pomotrelvir is a selective, competitive, orally active covalent inhibitor of the SARS-CoV-2 main protease (M pro), with an IC50 of 24 nM for wild-type SARS-CoV-2 M pro. Pomotrelvir inhibits viral polyprotein processing, thereby preventing viral replication. Pomotrelvir has shown broad antiviral activity against multiple SARS-CoV-2 variants (including Omicron) in cell-based experiments, and has an additive effect when combined with nucleoside analogs that target viral RNA synthesis. Pomotrelvir is primarily used for the research and development of COVID-19 antiviral drugs, especially for infections caused by SARS-CoV-2 and its variants .
Referencia número: HY-P991483
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Referencia número: HY-P991484
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Referencia número: HY-P991482
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Referencia número: HY-N144101
No. CAS: 81418-42-0
Category:
Infection Quinones Plants Lithospermum canescens Lehm. Disease Research Fields Boraginaceae Naphthalene Quinones
Target:
Referencia número: HY-P703548
Pureza: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Avian infectious bronchitis virus (strain M41); IBV; pp1a; Hydrolase; Lyase; Protease; RNA-binding; Thiol protease
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
