81418-42-0
Chemical Structure
SARS-CoV MPro-IN-2
- CAS No.: 81418-42-0
- Formula:C13H10O4
- Molecular Weight:230.22
IUPAC Name: 2-acetyl-8-methoxynaphthalene-1,4-dione
InChIKey: QASXCIRROULNNX-UHFFFAOYSA-N
SMILES: O=C1C(C(C)=O)=CC(C2=C1C(OC)=CC=C2)=O
Biological Activity: SARS-CoV MPro-IN-2 (compound 15) is a potent inhibitor of SARS-CoV-2 Mpro with an IC50 value of 72.07 nM. The main protease (Mpro) of the virus as the major enzyme processing viral polyproteins contributes to the replication and transcription of SARS-CoV-2 in host cells, and has been characterized as an attractive target in agent discovery. SARS-CoV MPro-IN-2 has the potential for the research of COVID-19[1].
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SARS-CoV MPro-IN-2 | SARS-CoV MPro-IN-2 (compound 15) is a potent inhibitor of SARS-CoV-2 Mpro with an IC50 value of 72.07 nM. The main protease (Mpro) of the virus as the major enzyme processing viral polyproteins contributes to the replication and transcription of SARS-CoV-2 in host cells, and has been characterized as an attractive target in agent discovery. SARS-CoV MPro-IN-2 has the potential for the research of COVID-19. | |||||||||||||||||||||
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Keywords
