SARS-CoV MPro-IN-2
SARS-CoV MPro-IN-2 (compound 15) is a potent inhibitor of SARS-CoV-2 Mpro with an IC50 value of 72.07 nM. The main protease (Mpro) of the virus as the major enzyme processing viral polyproteins contributes to the replication and transcription of SARS-CoV-2 in host cells, and has been characterized as an attractive target in agent discovery. SARS-CoV MPro-IN-2 has the potential for the research of COVID-19.
For research use only. We do not sell to patients.
- CAS No.: 81418-42-0
- Formula: C13H10O4
- Molecular Weight:230.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HFF-1 | IC50 |
41.2 μM
Compound: 15
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Cytotoxicity against HFF-1 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
Cytotoxicity against HFF-1 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
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[PMID: 34438124] |
Chemical Information
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CAS No. 81418-42-0
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Molecular Weight 230.22
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Formula C13H10O4
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SMILES
O=C1C(C(C)=O)=CC(C2=C1C(OC)=CC=C2)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SARS-CoV MPro-IN-2 Related Classifications
HY-N144101 Related Classifications
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