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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
Mannose6
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "Mannose6" in MCE Product Catalog:
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1 Cited Publications
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ML089 is an orally active inhibitor of phosphomannose isomerase (PMI) and PHOSPHO1, with an IC50 value of 1.3 μM against human PMI and an IC50 value of 0.8 μM against PHOSPHO1. ML089 blocks the catabolism of mannose-6-phosphate, directs mannose-6-phosphate to participate in protein glycosylation, increases mannose incorporation into cellular proteins, and reduces tritiated water production from mannose-6-phosphate. ML089 inhibits PMI in living cells. ML089 can be used in research related to congenital disorder of glycosylation type Ia (CDG-Ia) .
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DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates .
Cat. No.: HY-W718145
CAS No.: 70442-25-0
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Thr101 is an inhibitor (IC50=2.9 μM) of phosphomannose isomerase (PMI).PMI can compete with phosphomannose mutase 2 (PMM2) for the binding site of Man-6-P and convert mannose-6-phosphate (Man-6-P) into fructose-6-phosphate (Fru-6-P) .Thr101 only specifically inhibits PMI and not PMM2. Thr101 can be used for research of congenital disorder of glycosylation type Ia (CDG-Ia) .
Cat. No.: HY-W854355
CAS No.: 33068-18-7
Cat. No.: HY-158509
Synonyms: Mannose-6 N-linked oligosaccharide; OligoMannose 6 glycan
Cat. No.: HY-158514
Synonyms: Mannose-6 N-linked oligosaccharide, 2-AB labelled; OligoMannose 6 glycan, 2-AB labelled
Cat. No.: HY-158516
Synonyms: Mannose-6 N-linked oligosaccharide, procainamide labelled; OligoMannose 6 glycan, procainamide labelled
Cat. No.: HY-158511
Synonyms: Mannose-6 N-linked oligosaccharide, 2-AA labelled; OligoMannose 6 glycan, 2-AA labelled
Cat. No.: HY-101779A
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DCG04 isomer-1 is an isomer of DCG04 (HY-101779). DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates .
Phosphomannose isomerase is the first enzyme involved in the biosynthesis pathway of GDP-Man. Phosphomannose isomerase catalyzes the conversion between fructose-6-phosphate (Fru6P) and mannose-6-phosphate (Man6P). Phosphomannose isomerase is important for cell wall synthesis and protein glycosylation. Phosphomannose isomerase is a potent antifungal target to curb the threats posed by A. flavus .
Cat. No.: HY-P99803
CAS No.: 2145123-44-8
Synonyms: VAL-1221
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Cat. No.: HY-116514R
CAS No.: 18457-55-1
Cat. No.: HY-164396
CAS No.: 3030990-46-3
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Allyl-mannose-6-phosphonate is a stable analog of mannose-6-phosphate (M6P). Allyl-mannose-6-phosphonate can be used to synthesize M6Pn-polypeptide conjugates and construct lysosome-targeting chimeras (LYTAC). Allyl-mannose-6-phosphonate is applicable for tumor research .
Cat. No.: HY-P85506
Synonyms: PMI1; CDG1B; FLJ39201; Mannose 6 phosphate isomerase; Mannose-6-phosphate isomerase; MannosePHOSPHATE ISOMERASE; MGC94106; MPI; MPI_HUMAN; Phosphohexomutase; phosphoMannose isomerase 1; PhosphoMannose isomerase; PMI; PMI1.
Cat. No.: HY-P703904
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGF2R; CI Man-6-P Receptor; Insulin Like Growth Factor 2 Receptor; M6P/IGF2 Receptor; MPRI; IGF-II Receptor; CI-M6PR; M6P/IGF2R; CI-MPR; MPR 300; MPR300; Mannose 6-Phosphate/Insulin-Like Growth Factor-II Receptor; CD222; Cation-Independent Mannose-6 Phosp
Cat. No.: HY-P700869
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF2R; CI Man-6-P Receptor; Insulin Like Growth Factor 2 Receptor; M6P/IGF2 Receptor; MPRI; IGF-II Receptor; CI-M6PR; M6P/IGF2R; CI-MPR; MPR 300; MPR300; Mannose 6-Phosphate/Insulin-Like Growth Factor-II Receptor; CD222; Cation-Independent Mannose-6 Phosp
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
