314263-42-8
Chemical Structure
DCG04
- CAS No.: 314263-42-8
- Formula:C43H66N8O11S
- Molecular Weight:903.10
IUPAC Name: ethyl (2S,3S)-3-(((4S,7S,17S)-17-carbamoyl-7-(4-hydroxybenzyl)-2-methyl-5,8,15,23-tetraoxo-27-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9,16,22-tetraazaheptacosan-4-yl)carbamoyl)oxirane-2-carboxylate
InChIKey: MHOVYDVXSWUHAZ-JWZOSVBYSA-N
SMILES: OC(C=C1)=CC=C1C[C@@H](C(NCCCCCC(N[C@H](C(N)=O)CCCCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=O)=O)NC([C@H](CC(C)C)NC([C@@H]4[C@H](O4)C(OCC)=O)=O)=O
Biological Activity: DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DCG04 | 98.55% | DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates. | ||||||||||||||||||||
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DCG04 (Standard) | ≥98% | DCG04 (Standard) is the analytical standard of DCG04 (HY-101779). This product is intended for research and analytical applications. DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, and can be used for labelling numerous cysteine cathepsins in cell and tissue lysates. | ||||||||||||||||||||
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- [1]. Hillaert U, et al. Receptor-mediated targeting of cathepsins in professional antigen presenting cells [published correction appears in Angew Chem Int Ed Engl. 2009;48(14):2442.. Saragliadis, Anastasios [corrected to Saragliadis, Athanasios]]. Angew Chem Int Ed Engl. 2009;48(9):1629-1632. [Content Brief]
- [2]. Paulick MG, et al. Development of activity-based probes for cathepsin X. ACS Chem Biol. 2011;6(6):563-572. [Content Brief]
Keywords
