Allyl-mannose-6-phosphonate
Allyl-mannose-6-phosphonate is a stable analog of mannose-6-phosphate (M6P). Allyl-mannose-6-phosphonate can be used to synthesize M6Pn-polypeptide conjugates and construct lysosome-targeting chimeras (LYTAC). Allyl-mannose-6-phosphonate is applicable for tumor research.
For research use only. We do not sell to patients.
- CAS No.: 3030990-46-3
- Formula: C10H19O8P
- Molecular Weight:298.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Allyl-mannose-6-phosphonate (Compound 6) incorporated into tetrameric conjugates offers the best balance of synthetic simplicity and NA-650 uptake efficacy in Huh7 cells, with hexameric conjugates showing the highest overall uptake and lower-valency conjugates showing minimal to no uptake[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3030990-46-3
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Molecular Weight 298.23
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Formula C10H19O8P
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SMILES
O=P(O)(O)CC[C@H]1O[C@@H]([C@H]([C@H]([C@@H]1O)O)O)OCC=C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)