7 Results for "

Manumycin A

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Manumycin A" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N6796
CAS No.: 52665-74-4
Manumycin A is a polyketide antibiotic and an inhibitor of thioredoxin reductase 1 (TrxR-1). Manumycin A can inhibit the growth of breast cancer cells and exert its anti-tumor activity through LC3. Manumycin A can downregulate the release of pro-inflammatory cytokines in human monocytes stimulated by TNF α, and has potential anti-inflammatory activity. Manumycin A can inhibit the Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration resistant prostate cancer cells to suppress exosome biogenesis and secretion .
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Cat. No.: HY-118893
CAS No.: 61116-33-4
Purity:  ≥95.0%
Asukamycin, a manumycin-type metabolite, could be isolated from Streptomyces nodosus subsp. asukaensis. Asukamycin is an antibiotic and has antimicrobial activity. Asukamycin inhibits growth of various tumor cell lines .
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Cat. No.: HY-123887
CAS No.: 139023-58-8
Manumycin B is an antibiobic, and exhibits antitumor activity. Manumycin B is an inhibitor for acetylcholinesterase (AChE) with an IC50 of 15 mM .
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Cat. No.: HY-N14344
CAS No.: 156250-44-1
Manumycin G has anti-Gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-Gram-negative bacteria, and has no effect on fungi. Manumycin G inhibits RAS Faraday base transfer and has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL) .
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Cat. No.: HY-N13892
CAS No.: 136398-54-4
Alisamycin is the manumycin group of antibiotic. Alisamycin is active against Gram-positive bacteria and fungi, and has a weak antitumour activity .
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Cat. No.: HY-N14342
CAS No.: 156250-43-0
Manumycin E has anti-Gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-Gram-negative bacteria, and has no effect on fungi. Manumycin E inhibits RAS Faraday base transfer and has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL) .
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Cat. No.: HY-N14343
CAS No.: 156317-47-4
Manumycin F has anti-Gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-Gram-negative bacteria, and has no effect on fungi. Manumycin F inhibits RAS Faraday base transfer and has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL) .
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