1 Result for "

Mca-PLGL-Dpa-AR-NH2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Mca-PLGL-Dpa-AR-NH2" in MCE Product Catalog:

Mca-PLGL-Dpa-AR-NH2
Mca-PLGL-Dpa-AR-NH2
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Cat. No.: HY-131498
CAS No.: 140430-53-1
Purity:  99.67%
Synonyms: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-ARg-NH2
Target:  

Fluorescent Dye MMP

Research Areas:  

Cancer

MOCAc-PLGL (Dpa) AR (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) is a synthetic fluorescent substrate mainly used for in vitro enzymatic activity assays of MMP-7 (detection at 393 nm after excitation at 328 nm). MOCAc-PLGL (Dpa) AR is specifically cleaved and hydrolyzed by MMP-7 at the Gly-Leu peptide bond, allowing enzymatic activity to be monitored via fluorometry or HPLC (DMSO is usually added to ensure sufficient dissolution when determining kinetic parameters). MOCAc-PLGL (Dpa) AR is used to accurately evaluate the catalytic activity and pH dependence of recombinant mature human MMP-7 in vitro. MOCAc-PLGL (Dpa) AR is suitable for research on the mechanisms of tumor metastasis and invasion, particularly in fields such as prostate cancer, colon cancer, lung cancer and breast cancer [2] .\n
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