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Metronidazole

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

4

Biochemical Assay Reagents

1

Peptides

4

Natural
Products

8

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0318
    Metronidazole
    60+ Cited Publications

    		 Environmental Pollutants Antibiotic Bacterial Apoptosis Parasite Infection Inflammation/Immunology Cancer
    Metronidazole is an orally active nitroimidazole antibiotic. Metronidazole can cross blood brain barrier. Metronidazole can be used for the research of anaerobic infections .
    Metronidazole
  • HY-122975
    Metronidazole Benzoate

    Benzoyl Metronidazole

    		 Bacterial Parasite Infection
    Metronidazole Benzoate, derives from a metronidazole and a benzoic acid, has a role as an antibacterial, antimicrobial, antiparasitic, and antitrichomonal agent .
    Metronidazole Benzoate
  • HY-W015551
    trans-2-Decenal

    (E)-Dec-2-enal

    		 Bacterial Reactive Oxygen Species (ROS) Infection
    trans-2-Decenal ((E)-Dec-2-enal) acts as a urease inhibitor and antibacterial agent against Helicobacter pylori, with an IC50 of 9.484 μg/mL against Helicobacter pylori urease. trans-2-Decenal reduces the urease activity of Helicobacter pylori, and possesses antibacterial, bactericidal, anti-biofilm and anti-migratory activities. It alters the morphology of Helicobacter pylori, induces bacterial rupture, inhibits biofilm formation, reduces the number of mature biofilms and impairs the migratory capacity of Helicobacter pylori. trans-2-Decenal disrupts the cell wall integrity of Phytophthora capsici, damages membrane integrity and permeability, triggers intracellular reactive oxygen species (ROS) accumulation, decreases glutathione levels and disrupts the mitochondrial membrane potential of Phytophthora capsici. trans-2-Decenal is applicable to studies related to Helicobacter pylori and plant diseases induced by and Phytophthora capsici .
    trans-2-Decenal
  • HY-115249
    Metronidazole acetic acid

    		Bacterial Infection
    Metronidazole acetic acid is a metabolite of Metronidazole (HY-B0318) and exhibits mutagenic activity in bacterial .
    Metronidazole acetic acid
  • HY-B0318S2
    Metronidazole-d3

    		Isotope-Labeled Compounds Bacterial Parasite Apoptosis Antibiotic Infection
    Metronidazole-d3 is deuterium labeled Metronidazole.
    Metronidazole-d3
  • HY-B0318R
    Metronidazole (Standard)

    		Reference Standards Bacterial Parasite Apoptosis Antibiotic Infection Inflammation/Immunology Cancer
    Metronidazole (Standard) is the analytical standard of Metronidazole. This product is intended for research and analytical applications. Metronidazole is an orally active nitroimidazole antibiotic. Metronidazole can cross blood brain barrier. Metronidazole can be used for the research of anaerobic infections .
    Metronidazole (Standard)
  • HY-B0318S
    Metronidazole-13C2,15N2
    1 Publications Verification

    		 Bacterial Parasite Apoptosis Antibiotic Infection
    Metronidazole- 13C2, 15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
    Metronidazole-13C2,15N2
  • HY-B0318A
    Metronidazole hydrochloride
    Maximum Cited Publications
    65 Publications Verification

    SC 326421

    		 Antibiotic Bacterial Parasite Apoptosis Infection Inflammation/Immunology Cancer
    Metronidazole hydrochloride (SC 326421) is an orally active nitroimidazole antibiotic, can be used to research anaerobic infections. Metronidazole hydrochloride can cross blood brain barrier and results inflammation and skeletal muscle contraction under long-term application .
    Metronidazole hydrochloride
  • HY-B0318S1
    Metronidazole-d4

    		Bacterial Parasite Apoptosis Antibiotic Infection
    Metronidazole-d4 is the deuterium labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
    Metronidazole-d4
  • HY-P5640
    Tritrpticin

    		Bacterial Parasite Infection
    Tritrpticin is a porcine-derived antimicrobial peptide with properties such as membrane disruption and hemolysis. Tritrpticin disrupts the cell membranes of bacteria, fungi and Jurkat T cell leukemia cells and induces their death. Tritrpticin also enhances the efficacy of Metronidazole (HY-B0318) against *Trichomonas vaginalis*, reduces plasma endotoxin and inflammatory cytokine levels, restricts bacterial growth in blood and visceral tissues, decreases the mortality rate of septic shock in rats and enhances the therapeutic effect of ertapenem. Tritrpticin exhibits selective cytotoxicity against Jurkat T cell leukemia cells, while showing low toxicity to normal peripheral blood mononuclear cells and red blood cells, and can serve as a template for antimicrobial peptide design. Tritrpticin can be applied to research related to bacterial infections, fungal infections, trichomoniasis, septic shock and leukemia .
    Tritrpticin
  • HY-136440
    Hydroxymetronidazole

    Metronidazole-OH

    		 Bacterial Parasite Infection
    Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
    Hydroxymetronidazole
  • HY-136440R
    Hydroxymetronidazole (Standard)

    Metronidazole-OH (Standard)

    		 Reference Standards Bacterial Parasite Infection
    Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
    Hydroxymetronidazole (Standard)
  • HY-163060
    Metronidazole phosphate disodium

    		Drug Derivative Antibiotic Bacterial Infection
    Metronidazole phosphate disodium is a water-soluble prodrug for parenteral solutions of Metronidazole (HY-B0318). Metronidazole phosphate disodium is an antibiotic and can be used for the research of anaerobic infections .
    Metronidazole phosphate disodium
  • HY-115249R
    Metronidazole acetic acid (Standard)

    		Parasite Antibiotic Bacterial Reference Standards Infection
    Metronidazole acetic acid (Standard) is the analytical standard of Metronidazole acetic acid. This product is intended for research and analytical applications. Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
    Metronidazole acetic acid (Standard)
  • HY-138094
    N-(2-Hydroxyethyl)oxamic acid

    		Drug Metabolite Infection
    N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria .
    N-(2-Hydroxyethyl)oxamic acid
  • HY-122975R
    Metronidazole Benzoate (Standard)

    Benzoyl Metronidazole (Standard)

    		 Reference Standards Bacterial Parasite Infection
    Metronidazole Benzoate (Standard) is the analytical standard of Metronidazole Benzoate. This product is intended for research and analytical applications. Metronidazole Benzoate, derives from a metronidazole and a benzoic acid, has a role as an antibacterial, antimicrobial, antiparasitic, and antitrichomonal agent .
    Metronidazole Benzoate (Standard)
  • HY-B1118S
    Secnidazole-d6

    RP-14539-d6; PM-185184-d6

    		 Isotope-Labeled Compounds Parasite Antibiotic Infection
    Secnidazole-d6 is the deuterium labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research .
    Secnidazole-d6
  • HY-171956
    Carmaphycin-17

    		Proteasome Parasite Infection
    Carmaphycin-17 (CP-17) is a selective 20S proteasome inhibitor with an EC50 of 217 ?nM. Carmaphycin-17 has potent antimicrobial activity against Trichomonas vaginalis. Carmaphycin-17 overcomes Metronidazole (HY-B0318) resistance and significantly reduces parasite burden upon topical treatment without any apparent adverse effects in vaginal trichomonad infection mice model. Carmaphycin-17 can be used for sexually transmitted disease like trichomoniasis research .
    Carmaphycin-17
  • HY-B0318AS
    Metronidazole-d4 hydrochloride

    SC 326421-d4

    		 Isotope-Labeled Compounds Antibiotic Others
    Metronidazole-d4 (hydrochloride) is the deuterium labeled Metronidazole hydrochloride .
    Metronidazole-d4 hydrochloride
  • HY-161581
    Metronidazole/OVA

    		Biochemical Assay Reagents Inflammation/Immunology
    Metronidazole/OVA is a conjugate of Metronidazole (HY-B0318) and Ovalbumin (OVA). By conjugating the antigen with protein adjuvants, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt the primary epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.
    Metronidazole/OVA
  • HY-161548
    Metronidazole/KLH

    		Biochemical Assay Reagents Inflammation/Immunology
    Metronidazole/KLH is a conjugate of Metronidazole (HY-B0318) and Keyhole Limpet Hemocyanin (KLH). By conjugating the antigen with the protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes and can enhance cross-presentation and the generation of antigen-specific T cells.
    Metronidazole/KLH
  • HY-163553
    Metronidazole/BSA

    		Biochemical Assay Reagents Inflammation/Immunology
    Metronidazole/BSA is an antigen-adjuvant conjugate of Metronidazole (HY-B0318) and Bovine Serum Albumin (BSA). By conjugating the antigen with the protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and it can enhance cross-presentation and the production of antigen-specific T cells.
    Metronidazole/BSA
  • HY-136440S
    Hydroxymetronidazole-d4

    Metronidazole-OH-d4

    		 Isotope-Labeled Compounds Bacterial Parasite Infection
    Hydroxymetronidazole-d4 is the deuterium labeled Hydroxymetronidazole. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
    Hydroxymetronidazole-d4
  • HY-136440S1
    Hydroxymetronidazole-d2

    Metronidazole-OH-d2

    		 Isotope-Labeled Compounds Infection
    Hydroxymetronidazole-d2 is the deuterium labeled Hydroxymetronidazole(HY-136440).Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
    Hydroxymetronidazole-d2
  • HY-131257R
    Gefitinib impurity 1 (Standard)

    		Drug Metabolite Reference Standards Others Cancer
    Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .
    Gefitinib impurity 1 (Standard)
  • HY-W143313
    1,2-Heptanediol

    1,2-Dihydroxyheptane

    		 Biochemical Assay Reagents Others
    1,2-Heptanediol is one of the components of some formulations (F11 and F12). 1,2-Heptanediol can be used in absorption studies of Metronidazole (HY-B0318) .
    1,2-Heptanediol
  • HY-129662
    Ro 31-0052

    		Biochemical Assay Reagents Others
    Ro 31-0052 is a basic radiation sensitizer, a 3'-hydroxypiperidine analog of Ro 03-8799, with improved hydrophilicity. This type of designed radiation sensitizer has better pharmacokinetic properties and has the potential to replace clinically used Misonidazole (HY-105061) and Metronidazole (HY-B0318) .
    Ro 31-0052
  • HY-B1118S1
    Secnidazole-13C2, 15N2

    RP-14539-13C2, 15N2; PM-185184-13C2, 15N2

    		 Isotope-Labeled Compounds Parasite Antibiotic Infection
    Secnidazole- 13C2, 15N2 is the 13C2, 15N2 labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research.
    Secnidazole-13C2, 15N2
  • HY-W015509
    Metronidazole impurity 1

    		Drug Intermediate Others
    Metronidazole impurity 1 is an impurity of Metronidazole (HY-B0318).
    Metronidazole impurity 1
  • HY-W010433
    Metronidazole impurity 2

    2-Methyl-5-nitro-1H-imidazole

    		 Drug Intermediate Others
    Metronidazole impurity 2 (2-Methyl-5-nitro-1H-imidazole) is an impurity of Metronidazole.
    Metronidazole impurity 2
  • HY-W015509R
    Metronidazole impurity 1 (Standard)

    		Reference Standards
    2-(5-Nitro-1H-imidazol-1-yl)ethanol (Standard) is the analytical standard of 2-(5-Nitro-1H-imidazol-1-yl)ethanol. This product is intended for research and analytical applications.
    Metronidazole impurity 1 (Standard)
  • HY-116880
    DS-2969b

    		Bacterial DNA/RNA Synthesis Infection
    DS-2969b is an orally active GyrB inhibitor with antibacterial activity. DS-2969b is is active against Clostridium difficile infection (MIC90: 0.06 μg/mL), which is 2-, 16-, and 32-fold lower than those of Fidaxomicin (HY-17580), Metronidazole (HY-B0318), and Vancomycin (HY-B0671), respectively. DS-2969b inhibits the supercoiling activity of C. difficile DNA gyrase. DS-2969b also exhibits activity against other Gram-positive anaerobes, including strict and facultative anaerobes. DS-2969b is safe and well tolerated in preclinical toxicology studies .
    DS-2969b

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