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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
Myelin Basic Protein
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "Myelin Basic Protein" in MCE Product Catalog:
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Glatiramer acetate, a synthetic analogue of myelin basic protein and an immunomodulating agent, inhibits Experimental autoimmune encephalomyelitis (EAE), and can be used for the research of multiple sclerosis. Glatiramer acetate exhibits strong and promiscuous binding to MHC molecules and consequent competition with various myelin antigens for their presentation to T cells. A further aspect of its action is potent induction of specific suppressor cells of the T helper 2 (Th2) type that migrate to the brain and lead to in situ bystander suppression .
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PD 174265 is a highly selective, reversible EGFR/ErbB2 tyrosine kinase inhibitor (IC50=0.45 nM) and cell differentiation inducer. By blocking receptor autophosphorylation and the downstream ERK signaling pathway (with an IC50 of 0.45 μM for full-length ERK), PD 174265 effectively inhibits tumor growth and exhibits antitumor activity without obvious toxicity in in vivo models. PD 174265 drives oligodendrocyte precursor cells to switch from a proliferative state to a differentiated state, significantly upregulates the expression of myelin proteins such as CNP, PLP and MBP, and induces neurite branching. PD 174265 shows no inhibitory effect on other kinases including insulin, PDGF and basic FGF receptors, and serves as a crucial tool molecule for investigating the treatment of human epidermoid carcinoma and the mechanism of myelin repair in multiple sclerosis .
Cat. No.: HY-P3828
CAS No.: 923949-88-6
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Cat. No.: HY-P10532
CAS No.: 121196-80-3
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Cat. No.: HY-P3739
CAS No.: 136132-68-8
Cat. No.: HY-P3073
CAS No.: 106128-98-7
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Cat. No.: HY-P1048
CAS No.: 98474-59-0
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Cat. No.: HY-P1996
CAS No.: 178823-49-9
Synonyms: NBI-5788
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Cat. No.: HY-P3724
CAS No.: 604803-17-0
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Cat. No.: HY-P3817
CAS No.: 98474-60-3
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Cat. No.: HY-P1052
CAS No.: 118506-26-6
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Cat. No.: HY-P1052A
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Cat. No.: HY-P3248
CAS No.: 444305-16-2
Synonyms: Myelin Basic Protein (85-99) antagonist
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Cat. No.: HY-P3541
CAS No.: 152074-97-0
Synonyms: MBP8298
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Cat. No.: HY-NP208
Cat. No.: HY-P1734
CAS No.: 125366-42-9
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H3R antagonist 1 is a histamine receptor 3 (H3R) inverse agonist. H3R antagonist 1 increases the expression levels of myelin-associated glycoprotein (MAG) and myeline basic protein (MBP) in differentiating oligodendrocytes. H3R antagonist 1 can be used for the study of multiple sclerosis .
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H3R antagonist 1 hydrochloride is a histamine receptor 3 (H3R) inverse agonist. H3R antagonist 1 hydrochloride increases the expression levels of myelin-associated glycoprotein (MAG) and myeline basic protein (MBP) in differentiating oligodendrocytes. H3R antagonist 1 hydrochloride can be used for the study of multiple sclerosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
