444305-16-2
Chemical Structure
J5 peptide
Synonym(s): Myelin basic protein (85-99) antagonist
- CAS No.: 444305-16-2
- Formula:C70H114N18O21
- Molecular Weight:1543.76
InChIKey: VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES: OC(CC[C@H](N)C(N[C@@H](CCCCN)C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: J5 peptide is an MBP inhibitor that competitively inhibits the binding of MBP85-99 to HLA-DR2. J5 peptide alleviates PLP139-151/MBP85-99-induced experimental autoimmune encephalomyelitis (EAE) in mice. J5 peptide can be used in research on inflammatory and immune diseases[1].
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J5 peptide | J5 peptide is an MBP inhibitor that competitively inhibits the binding of MBP85-99 to HLA-DR2. J5 peptide alleviates PLP139-151/MBP85-99-induced experimental autoimmune encephalomyelitis (EAE) in mice. J5 peptide can be used in research on inflammatory and immune diseases. | |||||||||||||||||||||
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