13 Results for "

Naphthyridine

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "Naphthyridine" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P0171
CAS No.: 664334-36-5
Synonyms: BKT140 (4-fluorobenzoyl); BL-8040; TF14016
Target:  

CXCR

Research Areas:  

Endocrinology Cancer

Motixafortide (BKT140 4-fluorobenzoyl) is a novel CXCR4 antagonist with an IC50 vakue of ~1 nM.
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2
2 Cited Publications
Cat. No.: HY-P0009A
CAS No.: 145672-81-7
Synonyms: SB-75 acetate
Target:  

GnRH Receptor Apoptosis

Research Areas:  

Endocrinology

Cetrorelix (SB-75) acetate is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix acetate inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix acetate prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix acetate is applicable for fertility assistance research .
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1
1 Cited Publications
Cat. No.: HY-P4452
CAS No.: 209006-18-8
Research Areas:  

Endocrinology

PRL 2915 is a potent human somatostatin subtype 2 receptor (hsst2) antagonist with a Ki of 12 nM .
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Cat. No.: HY-153804
CAS No.: 864627-58-7
Purity:  99.68%
Synonyms: NCD
Target:  

Molecular Glues

Research Areas:  

Others Cancer

Naphthyridine caebamate dimer (NCD) is a DNA molecular glue that induces designed structural changes in target functional DNA to modulate function .
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Cat. No.: HY-W002277
CAS No.: 254-60-4
Target:  

Drug Derivative

Research Areas:  

Infection Cancer

1,8-Naphthyridine is a heterocyclic compound with antibacterial and antitumor activities. 1,8-Naphthyridine is promising for research of antibacterial agents and cancers .
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Cat. No.: HY-P0009B
CAS No.: 130143-01-0
Synonyms: SB-75 diacetate
Target:  

GnRH Receptor

Research Areas:  

Neurological Disease Endocrinology

Cetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM .
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Cat. No.: HY-W003037
CAS No.: 113118-81-3
Synonyms: 5-Bromo-3-pyridinecarboxaldehyde
5-Bromonicotinaldehyde (5-Bromo-3-pyridinecarboxaldehyde) can replace anilines (anilines) compounds and is used in the synthesis of naphthyridines and diazobenzenes .
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Cat. No.: HY-178923
Research Areas:  

Infection

NNRT-IN-14 is an HIV-1 reverse transcriptase inhibitor (IC50 = 0.175 µM). NNRT-IN-14 can form hydrogen bonds with LYS101, PRO225, and PHE227, and π–π stacking with TYR181 and TRP229. NNRT-IN-14 can be used for the study of HIV .
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Cat. No.: HY-131374
CAS No.: 368874-31-1
Target:  

CXCR

Research Areas:  

Cancer

TN14003 is a CXCR4 inhibitor. TN14003 has antitumor activity .
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Cat. No.: HY-133787
CAS No.: 117678-38-3
Purity:  98.28%
Target:  

Drug Metabolite

Research Areas:  

Infection Others

Levofloxacin N-oxide is an oxidation product and impurity of Levofloxacin (HY-B0330), and it is a non-mutagen. Under specific concentration conditions with the addition of S-9 mixture, Levofloxacin N-oxide increases structural chromosomal aberrations in hamster lung cells .
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Cat. No.: HY-W034955
CAS No.: 69110-33-4
Target:  

MOFs

Research Areas:  

Others

2,2'-bi(1,8-naphthyridine) (2,2-BI(1,8-Naphthyridine)) is a metal-organic framework (MOF).
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Cat. No.: HY-150060
CAS No.: 524734-30-3
Research Areas:  

Inflammation/Immunology

PDE4-IN-11 is an inhibitor of phosphodiesterase isoenzyme 4 (PDE4). PDE4-IN-11 displays highly effective bronchodilatory and anti-inflammatory properties, can be used for obstructive or inflammatory airway diseases research .
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Cat. No.: HY-183664
CAS No.: 162424-67-1
Target:  

Bacterial

Research Areas:  

Infection

Ecenofloxacin hydrochloride is a fluoroquinolone (naphthyridine) antibacterial agent with broad-spectrum activity against Gram-negative, Gram-positive, and anaerobic bacteria .
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