Levofloxacin N-oxide
Based on 1 Customer Validation
Levofloxacin N-oxide is an oxidation product and impurity of Levofloxacin (HY-B0330), and it is a non-mutagen. Under specific concentration conditions with the addition of S-9 mixture, Levofloxacin N-oxide increases structural chromosomal aberrations in hamster lung cells.
For research use only. We do not sell to patients.
- Purity: 98.28%
- CAS No.: 117678-38-3
- Formula: C18H20FN3O5
- Molecular Weight:377.37
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Levofloxacin N-oxide (250-1000 μg/mL; 6 h) induces structural chromosomal aberrations in CHL cells only at a concentration of 1000 μg/mL under conditions metabolically activated by the S-9 mixture[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 117678-38-3
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Appearance Solid
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Molecular Weight 377.37
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Formula C18H20FN3O5
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Color White to off-white
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SMILES
O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CC[N+](C)([O-])CC4)C(F)=CC1=C23)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (132.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6499 mL | 13.2496 mL | 26.4992 mL | 66.2480 mL |
| 5 mM | 0.5300 mL | 2.6499 mL | 5.2998 mL | 13.2496 mL | |
| 10 mM | 0.2650 mL | 1.3250 mL | 2.6499 mL | 6.6248 mL | |
| 15 mM | 0.1767 mL | 0.8833 mL | 1.7666 mL | 4.4165 mL | |
| 20 mM | 0.1325 mL | 0.6625 mL | 1.3250 mL | 3.3124 mL | |
| 25 mM | 0.1060 mL | 0.5300 mL | 1.0600 mL | 2.6499 mL | |
| 30 mM | 0.0883 mL | 0.4417 mL | 0.8833 mL | 2.2083 mL | |
| 40 mM | 0.0662 mL | 0.3312 mL | 0.6625 mL | 1.6562 mL | |
| 50 mM | 0.0530 mL | 0.2650 mL | 0.5300 mL | 1.3250 mL | |
| 60 mM | 0.0442 mL | 0.2208 mL | 0.4417 mL | 1.1041 mL | |
| 80 mM | 0.0331 mL | 0.1656 mL | 0.3312 mL | 0.8281 mL | |
| 100 mM | 0.0265 mL | 0.1325 mL | 0.2650 mL | 0.6625 mL |
Levofloxacin N-oxide Related Classifications
HY-133787 Related Classifications
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