524734-30-3
Chemical Structure
PDE4-IN-11
- CAS No.: 524734-30-3
- Formula:C21H19FN2O2
- Molecular Weight:350.39
IUPAC Name: 4-(8-(3-fluorophenyl)-1,7-naphthyridin-6-yl)cyclohexane-1-carboxylic acid
InChIKey: XWVBOPKUSVZZPJ-UHFFFAOYSA-N
SMILES: O=C(C1CCC(CC1)C2=CC3=C(N=CC=C3)C(C4=CC=CC(F)=C4)=N2)O
Biological Activity: PDE4-IN-11 is an inhibitor of phosphodiesterase isoenzyme 4 (PDE4). PDE4-IN-11 displays highly effective bronchodilatory and anti-inflammatory properties, can be used for obstructive or inflammatory airway diseases research[1][2][3].
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PDE4-IN-11 | PDE4-IN-11 is an inhibitor of phosphodiesterase isoenzyme 4 (PDE4). PDE4-IN-11 displays highly effective bronchodilatory and anti-inflammatory properties, can be used for obstructive or inflammatory airway diseases research. | |||||||||||||||||||||
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- [1]. Denholm A, et al. Preparation of naphthyridines as phosphodiesterase isoenzyme 4 (PDE4) inhibitors: World Intellectual Property Organization, WO2003039544[P]. 2003-05-15.
- [2]. McCarthy C, et al. Use of naphthyridine derivatives as medicaments for the treatment of pulmonary hypertension: World Intellectual Property Organization, WO2007088019[P]. 2007-08-09.
- [3]. Press NJ, et al. Organic compounds for treating pulmonary hypertension: World Intellectual Property Organization, WO2009013286. 2009-01-29.
Keywords